|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$820M
|
+$19.1M
|
+678,704
|
+3%
|
|
|
2
|
|
$461M
|
+$73.2M
|
+2,605,056
|
+25%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$409M
|
+$106M
|
+3,756,664
|
+48%
|
|
|
4
|
Deerfield Management
New York
|
$321M
|
-$259K
|
-9,215
|
-0.1%
|
|
|
5
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$320M
|
–
|
–
|
–
|
|
|
6
|
|
$270M
|
+$116M
|
+4,124,755
|
+119%
|
|
|
7
|
Kynam Capital Management
Princeton,
New Jersey
|
$219M
|
-$48.4M
|
-1,720,949
|
-22%
|
|
|
8
|
TCG Crossover Management
Palo Alto,
California
|
$208M
|
-$26.1M
|
-930,000
|
-14%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$175M
|
+$4.64M
|
+164,881
|
+3%
|
|
|
10
|
Janus Henderson Group
London,
|
$161M
|
+$38.2M
|
+1,359,365
|
+43%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$125M
|
+$6.76M
|
+240,407
|
+7%
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$96.3M
|
+$64.8M
|
+2,305,437
|
+567%
|
|
|
13
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$91.1M
|
+$69.6M
|
+2,474,346
|
+2,758%
|
|
|
14
|
Vivo Capital
Palo Alto,
California
|
$85.2M
|
-$11M
|
-390,144
|
-14%
|
|
|
15
|
Octagon Capital Advisors
New York
|
$83.5M
|
-$14.7M
|
-524,111
|
-18%
|
|
|
16
|
|
$79.8M
|
+$20.2M
|
+716,879
|
+47%
|
|
|
17
|
Duquesne Family Office
New York
|
$78.7M
|
+$32.5M
|
+1,154,890
|
+109%
|
|
|
18
|
Commodore Capital
New York
|
$78M
|
-$142M
|
-5,053,155
|
-70%
|
|
|
19
|
|
$71M
|
-$56.2M
|
-2,000,000
|
-50%
|
|
|
20
|
Sofinnova Investments
Menlo Park,
California
|
$70.1M
|
-$4.34M
|
-154,316
|
-7%
|
|
|
21
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$66.4M
|
+$52.6M
|
+1,870,537
|
New
|
|
|
22
|
|
$60.6M
|
+$1.28M
|
+45,467
|
+3%
|
|
|
23
|
Marshall Wace
London,
United Kingdom
|
$59M
|
+$28.6M
|
+1,018,256
|
+158%
|
|
|
24
|
Siren LLC
Greenwich,
Connecticut
|
$57.9M
|
-$2.67M
|
-95,000
|
-6%
|
|
|
25
|
Emerald Advisers
Leola,
Pennsylvania
|
$56.2M
|
+$108K
|
+3,850
|
+0.2%
|
|
