|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$322M
|
+$63.1M
|
+5,329,795
|
+31%
|
|
|
2
|
|
$149M
|
+$20.6M
|
+1,742,954
|
+20%
|
|
|
3
|
Deerfield Management
New York
|
$130M
|
+$76M
|
+6,412,903
|
+243%
|
|
|
4
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$129M
|
+$32.9M
|
+2,777,777
|
+45%
|
|
|
5
|
Kynam Capital Management
Princeton,
New Jersey
|
$113M
|
-$7.18M
|
-606,385
|
-7%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$111M
|
+$14.6M
|
+1,234,711
|
+19%
|
|
|
7
|
Commodore Capital
New York
|
$104M
|
+$58.5M
|
+4,938,836
|
+214%
|
|
|
8
|
TCG Crossover Management
Palo Alto,
California
|
$97.6M
|
-$1.97M
|
-166,213
|
-2%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$68.6M
|
+$16.6M
|
+1,403,507
|
+42%
|
|
|
10
|
|
$57.4M
|
-$8.95M
|
-755,411
|
-16%
|
|
|
11
|
|
$49.8M
|
+$41.1M
|
+3,467,486
|
New
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$47M
|
+$7.13M
|
+602,042
|
+23%
|
|
|
13
|
Janus Henderson Group
London,
|
$45.6M
|
+$3.61M
|
+304,990
|
+11%
|
|
|
14
|
Paradigm Biocapital Advisors
New York
|
$45.3M
|
-$85.3M
|
-7,196,051
|
-70%
|
|
|
15
|
Octagon Capital Advisors
New York
|
$41.3M
|
+$1.32M
|
+111,111
|
+4%
|
|
|
16
|
Vivo Capital
Palo Alto,
California
|
$40.1M
|
+$19.7M
|
+1,666,666
|
+148%
|
|
|
17
|
Balyasny Asset Management
Chicago,
Illinois
|
$38.3M
|
+$31.6M
|
+2,670,486
|
New
|
|
|
18
|
Bank of America
Charlotte,
North Carolina
|
$32.2M
|
+$9.93M
|
+838,290
|
+60%
|
|
|
19
|
Redmile Group
San Francisco,
California
|
$31.7M
|
+$9.02M
|
+761,078
|
+53%
|
|
|
20
|
Sofinnova Investments
Menlo Park,
California
|
$30.6M
|
-$2.7M
|
-227,564
|
-10%
|
|
|
21
|
Saturn V Capital Management
Austin,
Texas
|
$29.1M
|
-$3.23M
|
-272,483
|
-12%
|
|
|
22
|
UBS Group
Zurich,
Switzerland
|
$26.6M
|
-$19.7M
|
-1,664,999
|
-47%
|
|
|
23
|
Siren LLC
Greenwich,
Connecticut
|
$24.8M
|
+$10.3M
|
+869,900
|
+102%
|
|
|
24
|
Citadel Advisors
Miami,
Florida
|
$23.9M
|
+$12.4M
|
+1,046,572
|
+168%
|
|
|
25
|
|
$23.8M
|
+$5.44M
|
+459,240
|
+38%
|
|
