|
1
|
Palo Alto Investors
Palo Alto,
California
|
$248M
|
+$5.52M
|
+90,875
|
+2%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$209M
|
+$40.3M
|
+662,969
|
+25%
|
|
|
3
|
|
$194M
|
+$185M
|
+3,047,145
|
+118,797%
|
|
|
4
|
PointState Capital
New York
|
$129M
|
-$69.7M
|
-1,145,933
|
-36%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$119M
|
-$16.9M
|
-278,354
|
-13%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$116M
|
+$80.7M
|
+1,327,703
|
+271%
|
|
|
7
|
|
$104M
|
+$56.1M
|
+922,235
|
+129%
|
|
|
8
|
Consonance Capital Management
New York
|
$85M
|
-$84.9M
|
-1,396,420
|
-51%
|
|
|
9
|
Wellington Management Group
Boston,
Massachusetts
|
$84.8M
|
+$80.2M
|
+1,318,669
|
+10,144%
|
|
|
10
|
Balyasny Asset Management
Chicago,
Illinois
|
$69.7M
|
+$49.5M
|
+814,132
|
+290%
|
|
|
11
|
PFM Health Sciences
San Francisco,
California
|
$64.1M
|
-$16.6M
|
-272,383
|
-21%
|
|
|
12
|
Boxer Capital
San Diego,
California
|
$63.7M
|
+$9.12M
|
+150,000
|
+18%
|
|
|
13
|
Franklin Resources
San Mateo,
California
|
$62.3M
|
+$25M
|
+412,000
|
+73%
|
|
|
14
|
Redmile Group
San Francisco,
California
|
$61.9M
|
-$39.4M
|
-647,659
|
-40%
|
|
|
15
|
AllianceBernstein
Nashville,
Tennessee
|
$48M
|
+$43M
|
+708,082
|
+1,538%
|
|
|
16
|
|
$39.5M
|
-$5.37M
|
-88,352
|
-12%
|
|
|
17
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$38.5M
|
+$24.6M
|
+404,784
|
+203%
|
|
|
18
|
Two Sigma Investments
New York
|
$35.4M
|
+$32.5M
|
+534,325
|
+2,491%
|
|
|
19
|
Millennium Management
New York
|
$34M
|
-$32.9M
|
-541,548
|
-50%
|
|
|
20
|
Teachers Advisors
New York
|
$31.3M
|
+$4.29M
|
+70,582
|
+17%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$31M
|
+$3.93M
|
+64,644
|
+15%
|
|
|
22
|
|
$28.1M
|
+$8.86M
|
+145,709
|
+49%
|
|
|
23
|
|
$27.2M
|
+$19M
|
+313,266
|
+274%
|
|
|
24
|
|
$27.2M
|
+$10.9M
|
+179,057
|
+72%
|
|
|
25
|
Versant Venture Management
San Francisco,
California
|
$25.9M
|
–
|
–
|
–
|
|
