|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$308M
|
+$20.4M
|
+288,846
|
+7%
|
|
|
2
|
NEA Management Company
Timonium,
Maryland
|
$169M
|
–
|
–
|
–
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$169M
|
+$4.38M
|
+62,078
|
+3%
|
|
|
4
|
PFM Health Sciences
San Francisco,
California
|
$168M
|
+$38.2M
|
+541,630
|
+31%
|
|
|
5
|
Palo Alto Investors
Palo Alto,
California
|
$158M
|
+$1.34M
|
+19,000
|
+0.9%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$122M
|
+$17.6M
|
+249,857
|
+18%
|
|
|
7
|
OppenheimerFunds
New York
|
$111M
|
-$19.8M
|
-279,724
|
-16%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$79.1M
|
+$1.88M
|
+26,579
|
+3%
|
|
|
9
|
|
$74.3M
|
+$20.2M
|
+286,300
|
+40%
|
|
|
10
|
Redmile Group
San Francisco,
California
|
$66.9M
|
+$12.7M
|
+179,247
|
+25%
|
|
|
11
|
Clifton Park Capital Management
Wilmington,
Delaware
|
$61.4M
|
+$2.57M
|
+36,364
|
+5%
|
|
|
12
|
Versant Venture Management
San Francisco,
California
|
$60.5M
|
–
|
–
|
–
|
|
|
13
|
BlackRock Institutional Trust
San Francisco,
California
|
$53.4M
|
+$276K
|
+3,902
|
+0.5%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$50.4M
|
-$1.02M
|
-14,508
|
-2%
|
|
|
15
|
Visium Asset Management
New York
|
$48.8M
|
-$19.1M
|
-270,847
|
-29%
|
|
|
16
|
BB Biotech
Schaffhausen,
Switzerland
|
$45.9M
|
–
|
–
|
–
|
|
|
17
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$42.4M
|
+$1.18M
|
+16,685
|
+3%
|
|
|
18
|
TimesSquare Capital Management
New York
|
$36.9M
|
+$515K
|
+7,300
|
+1%
|
|
|
19
|
Janus Henderson Investors US
Denver,
Colorado
|
$24.4M
|
-$12.4M
|
-175,870
|
-35%
|
|
|
20
|
|
$23.9M
|
-$5.12M
|
-72,541
|
-18%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$21.7M
|
+$322K
|
+4,554
|
+2%
|
|
|
22
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$20.8M
|
-$9.32M
|
-132,011
|
-32%
|
|
|
23
|
Ameriprise
Minneapolis,
Minnesota
|
$19.2M
|
-$12.6M
|
-178,457
|
-41%
|
|
|
24
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$18.5M
|
-$12.3M
|
-174,300
|
-41%
|
|
|
25
|
EcoR1 Capital
San Francisco,
California
|
$18M
|
-$9.98M
|
-141,300
|
-37%
|
|
