|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$318M
|
-$45.3M
|
-529,250
|
-13%
|
|
|
2
|
PFM Health Sciences
San Francisco,
California
|
$238M
|
+$38.3M
|
+446,905
|
+20%
|
|
|
3
|
Palo Alto Investors
Palo Alto,
California
|
$211M
|
+$23.9M
|
+279,260
|
+13%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$196M
|
-$4.27M
|
-49,845
|
-2%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$158M
|
+$13M
|
+151,772
|
+9%
|
|
|
6
|
OppenheimerFunds
New York
|
$133M
|
+$1.72M
|
+20,140
|
+1%
|
|
|
7
|
NEA Management Company
Timonium,
Maryland
|
$100M
|
-$97.6M
|
-1,139,891
|
-50%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$91.3M
|
-$2.32M
|
-27,131
|
-3%
|
|
|
9
|
|
$88.3M
|
+$411K
|
+4,800
|
+0.5%
|
|
|
10
|
Clifton Park Capital Management
Wilmington,
Delaware
|
$72.7M
|
–
|
–
|
–
|
|
|
11
|
Cortland Advisers
Wilmington,
Delaware
|
$72.7M
|
+$70.8M
|
+826,919
|
New
|
|
|
12
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$71.5M
|
+$20.8M
|
+243,048
|
+43%
|
|
|
13
|
Redmile Group
San Francisco,
California
|
$66.7M
|
-$12.1M
|
-141,400
|
-16%
|
|
|
14
|
Visium Asset Management
New York
|
$66M
|
+$8.03M
|
+93,831
|
+14%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$62M
|
+$2.31M
|
+26,957
|
+4%
|
|
|
16
|
BlackRock Institutional Trust
San Francisco,
California
|
$60.7M
|
-$2.47M
|
-28,821
|
-4%
|
|
|
17
|
BB Biotech
Schaffhausen,
Switzerland
|
$54.3M
|
–
|
–
|
–
|
|
|
18
|
TimesSquare Capital Management
New York
|
$43.1M
|
-$543K
|
-6,345
|
-1%
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$42.4M
|
+$25.6M
|
+298,864
|
+163%
|
|
|
20
|
Versant Venture Management
San Francisco,
California
|
$35.8M
|
-$34.9M
|
-407,417
|
-50%
|
|
|
21
|
Janus Henderson Investors US
Denver,
Colorado
|
$29.1M
|
+$229K
|
+2,676
|
+0.8%
|
|
|
22
|
|
$27.6M
|
-$676K
|
-7,899
|
-2%
|
|
|
23
|
Consonance Capital Management
New York
|
$26.6M
|
+$25.9M
|
+303,131
|
New
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$25.3M
|
-$447K
|
-5,225
|
-2%
|
|
|
25
|
PointState Capital
New York
|
$22.4M
|
+$4.71M
|
+55,000
|
+28%
|
|
