|
1
|
Avoro Capital Advisors
New York
|
$154M
|
–
|
–
|
–
|
|
|
2
|
|
$116M
|
+$3.81M
|
+287,326
|
+4%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$103M
|
+$92M
|
+6,940,000
|
New
|
|
|
4
|
Janus Henderson Group
London,
|
$101M
|
-$12.5M
|
-943,103
|
-12%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$85.7M
|
+$7.94M
|
+598,707
|
+12%
|
|
|
6
|
Adage Capital Partners
Boston,
Massachusetts
|
$61.5M
|
-$3.66M
|
-276,292
|
-6%
|
|
|
7
|
Perceptive Advisors
New York
|
$60.3M
|
+$4.11M
|
+309,936
|
+8%
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$57.4M
|
+$663K
|
+50,000
|
+1%
|
|
|
9
|
Jennison Associates
New York
|
$53M
|
+$25M
|
+1,883,742
|
+113%
|
|
|
10
|
Franklin Resources
San Mateo,
California
|
$49.3M
|
+$476K
|
+35,907
|
+1%
|
|
|
11
|
Holocene Advisors
New York
|
$46.5M
|
+$41.3M
|
+3,117,685
|
New
|
|
|
12
|
Octagon Capital Advisors
New York
|
$45.8M
|
-$19.8M
|
-1,497,168
|
-33%
|
|
|
13
|
Point72 Asset Management
Stamford,
Connecticut
|
$36.2M
|
+$32.2M
|
+2,429,924
|
New
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$34.1M
|
-$299K
|
-22,549
|
-1%
|
|
|
15
|
Fred Alger Management
New York
|
$32.4M
|
+$28.8M
|
+2,172,309
|
New
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$31M
|
+$2.92M
|
+220,086
|
+12%
|
|
|
17
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$28.4M
|
+$24M
|
+1,809,280
|
+1,916%
|
|
|
18
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$27.4M
|
+$15.2M
|
+1,143,067
|
+164%
|
|
|
19
|
Foresite Capital Management IV
Larkspur,
California
|
$26.6M
|
–
|
–
|
–
|
|
|
20
|
Fidelity Investments
Boston,
Massachusetts
|
$23.4M
|
+$20.6M
|
+1,557,462
|
+13,560%
|
|
|
21
|
Novo Holdings A/S
Hellerup,
Denmark
|
$23.4M
|
-$5.75M
|
-433,479
|
-22%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
$17.3M
|
-$72.2K
|
-5,449
|
-0.5%
|
|
|
23
|
Affinity Asset Advisors
New York
|
$16.8M
|
+$1.05M
|
+79,258
|
+8%
|
|
|
24
|
Saturn V Capital Management
Austin,
Texas
|
$16.8M
|
-$840K
|
-63,342
|
-5%
|
|
|
25
|
Victory Capital Management
San Antonio,
Texas
|
$15.5M
|
+$13.1M
|
+988,683
|
+2,028%
|
|
