|
1
|
Avoro Capital Advisors
New York
|
$46.8M
|
–
|
–
|
–
|
|
|
2
|
|
$27.1M
|
+$3.08M
|
+572,244
|
+11%
|
|
|
3
|
Boxer Capital
San Diego,
California
|
$18.2M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$16.8M
|
+$1.44M
|
+267,407
|
+8%
|
|
|
5
|
Commodore Capital
New York
|
$13.5M
|
+$8.06M
|
+1,497,406
|
+101%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$9.85M
|
-$3.89M
|
-722,812
|
-25%
|
|
|
7
|
Millennium Management
New York
|
$9.32M
|
+$3.81M
|
+707,731
|
+53%
|
|
|
8
|
Foresite Capital Management IV
Larkspur,
California
|
$8.11M
|
–
|
–
|
–
|
|
|
9
|
Foresite Capital Management III
Larkspur,
California
|
$7.45M
|
–
|
–
|
–
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$7.18M
|
-$5.07M
|
-942,450
|
-37%
|
|
|
11
|
Adage Capital Partners
Boston,
Massachusetts
|
$6.58M
|
–
|
–
|
–
|
|
|
12
|
Dimensional Fund Advisors
Austin,
Texas
|
$6M
|
+$378K
|
+70,206
|
+6%
|
|
|
13
|
Two Sigma Advisers
New York
|
$5.98M
|
+$552K
|
+102,500
|
+8%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$5.86M
|
-$2.79M
|
-517,501
|
-29%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$5.25M
|
+$632K
|
+117,409
|
+11%
|
|
|
16
|
Two Sigma Investments
New York
|
$4.66M
|
-$475K
|
-88,241
|
-8%
|
|
|
17
|
|
$4.34M
|
-$1.64M
|
-304,228
|
-24%
|
|
|
18
|
Renaissance Technologies
New York
|
$4.04M
|
+$2.59M
|
+480,443
|
+117%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$3.13M
|
-$216K
|
-40,087
|
-5%
|
|
|
20
|
Sio Capital Management
New York
|
$2.55M
|
-$135K
|
-25,000
|
-4%
|
|
|
21
|
Versant Venture Management
San Francisco,
California
|
$2.47M
|
–
|
–
|
–
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$2.45M
|
+$105K
|
+19,421
|
+4%
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$2.36M
|
+$2.53M
|
+469,590
|
+927%
|
|
|
24
|
Nuveen
Charlotte,
North Carolina
|
$1.64M
|
+$182K
|
+33,867
|
+10%
|
|
|
25
|
DAFNA Capital Management
Los Angeles,
California
|
$1.53M
|
+$1.82M
|
+337,770
|
New
|
|
