|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$72.5M
|
+$40.5M
|
+3,256,597
|
+140%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$50.9M
|
+$11.5M
|
+925,925
|
+31%
|
|
|
3
|
Adage Capital Partners
Boston,
Massachusetts
|
$45.1M
|
+$2.43M
|
+195,474
|
+6%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$38.4M
|
+$11.8M
|
+953,300
|
+48%
|
|
|
5
|
Boxer Capital
San Diego,
California
|
$35.2M
|
+$21.1M
|
+1,700,000
|
+168%
|
|
|
6
|
Perceptive Advisors
New York
|
$33.7M
|
+$1.45M
|
+116,939
|
+4%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$33M
|
+$9.44M
|
+759,607
|
+43%
|
|
|
8
|
Foresite Capital Management IV
Larkspur,
California
|
$27.4M
|
-$1.77M
|
-142,633
|
-6%
|
|
|
9
|
Franklin Resources
San Mateo,
California
|
$23.4M
|
+$4.35M
|
+350,000
|
+24%
|
|
|
10
|
Foresite Capital Management III
Larkspur,
California
|
$20.3M
|
+$12M
|
+962,040
|
+160%
|
|
|
11
|
Deerfield Management
New York
|
$15.8M
|
+$15.1M
|
+1,213,181
|
New
|
|
|
12
|
|
$15.2M
|
+$5.95M
|
+478,524
|
+69%
|
|
|
13
|
Millennium Management
New York
|
$15.1M
|
+$13.6M
|
+1,094,594
|
+1,667%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$13.9M
|
+$4.65M
|
+374,148
|
+54%
|
|
|
15
|
Versant Venture Management
San Francisco,
California
|
$13.6M
|
–
|
–
|
–
|
|
|
16
|
Nexthera Capital
New York
|
$11.1M
|
+$3.93M
|
+316,118
|
+59%
|
|
|
17
|
Vivo Capital
Palo Alto,
California
|
$10.4M
|
+$9.94M
|
+800,000
|
New
|
|
|
18
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$9.09M
|
+$8.7M
|
+700,100
|
New
|
|
|
19
|
Opaleye Management
Boston,
Massachusetts
|
$8.64M
|
–
|
–
|
–
|
|
|
20
|
|
$7.71M
|
+$46.3K
|
+3,726
|
+0.6%
|
|
|
21
|
Omega Fund Management
Boston,
Massachusetts
|
$7.16M
|
–
|
–
|
–
|
|
|
22
|
Farallon Capital Management
San Francisco,
California
|
$7.14M
|
-$6.83M
|
-550,000
|
-50%
|
|
|
23
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$6.37M
|
+$497K
|
+40,000
|
+9%
|
|
|
24
|
|
$5.92M
|
-$1.28M
|
-103,400
|
-18%
|
|
|
25
|
|
$5.75M
|
+$5.23M
|
+420,936
|
+1,966%
|
|
