CalciMedica
CALC
31 hedge funds and large institutions have $24.2M invested in CalciMedica in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 5 increasing their positions, 8 reducing their positions, and 6 closing their positions.
121% more capital invested
Capital invested by funds: $10.9M → $24.2M (+$13.3M)
17% more first-time investments, than exits
New positions opened: 7 | Existing positions closed: 6
0% more funds holding
Funds holding: 31 → 31 (0)
0% less ownership
Funds ownership: 5.11% → 5.11% (-0%)
38% less repeat investments, than reductions
Existing positions increased: 5 | Existing positions reduced: 8
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BFM
Boothbay Fund Management
New York
|
+$300K |
| 2 |
PAM
PVG Asset Management
Golden,
Colorado
|
+$179K |
| 3 |
Vanguard Group
Malvern,
Pennsylvania
|
+$122K |
| 4 |
Jane Street
New York
|
+$74.9K |
| 5 |
Renaissance Technologies
New York
|
+$71.4K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Millennium Management
New York
|
-$76.2K |
| 2 |
Envestnet Asset Management
Chicago,
Illinois
|
-$52.7K |
| 3 |
TW
TritonPoint Wealth
Chevy Chase,
Maryland
|
-$46.5K |
| 4 |
XT
XTX Topco
George Town,
Cayman Islands
|
-$46.3K |
| 5 |
1WA
180 Wealth Advisors
Federal Way,
Washington
|
-$42.3K |
CALC Hedge Fund Activity: Q4 2025 in Review
31 of the 8,270 institutional investors tracked by Wall St. Rank reported a position in CalciMedica (CALC) for Q4 2025, worth a combined $24.2M — up 121% from $10.9M a quarter earlier.
Buyers outnumbered sellers: 7 funds opened new CALC positions and 6 closed out — a net gain of 1 holder — while 5 added to existing stakes and 8 trimmed.
The largest buyer was Boothbay Fund Management, opening a new position worth an estimated $300K. The largest seller was Millennium Management, cutting an estimated $76.2K.
- 31 institutional investors held CalciMedica (CALC) as of Q4 2025, unchanged from Q3 2025.
- Funds reported $24.2M of CalciMedica stock for Q4 2025, up 121% quarter-over-quarter.
- 7 funds opened new CalciMedica positions in Q4 2025 and 6 closed out, a net change of +1 holder.
- The largest CalciMedica buyer in Q4 2025 was Boothbay Fund Management, an estimated $300K added.
- The largest CalciMedica seller in Q4 2025 was Millennium Management, an estimated $76.2K sold.
Based on aggregated 13F filings for Q4 2025.