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CalciMedica
CALC

30 hedge funds and large institutions have $7.49M invested in CalciMedica in 2025 Q1 according to their latest regulatory filings, with 4 funds opening new positions, 8 increasing their positions, 6 reducing their positions, and 3 closing their positions.

New
Increased
Maintained
Reduced
Closed

33% more first-time investments, than exits

New positions opened: 4 | Existing positions closed: 3

33% more repeat investments, than reductions

Existing positions increased: 8 | Existing positions reduced: 6

3% more funds holding

Funds holding: 29 → 30 (+1)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

2.2% less ownership

Funds ownership: 31.63% → 29.44% (-2.2%)

50% less capital invested

Capital invested by funds: $15.1M → $7.49M (-$7.6M)

Holders
30
Holders Change
+1
Holders Change %
+3.45%
% of All Funds
0.4%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
4
Increased
8
Reduced
6
Closed
3
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
WIA
Wealthedge Investment Advisors
New York
+$201K
2
PAM
PVG Asset Management
Colorado
+$75.7K
3
Cambridge Investment Research Advisors
Cambridge Investment Research Advisors
Iowa
+$58.7K
4
1WA
180 Wealth Advisors
Washington
+$40.9K
5
First Manhattan
First Manhattan
New York
+$33K

Top Sellers

1
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$1.32M
2
SCM
Stonepine Capital Management
Oregon
-$253K
3
Millennium Management
Millennium Management
New York
-$31.6K
4
Renaissance Technologies
Renaissance Technologies
New York
-$19.4K
5
Russell Investments Group
Russell Investments Group
United Kingdom
-$1.77K
Name Holding Trade Value Shares
Change 		Change in
Stake
DM
1
Deerfield Management
New York
$2.48M – – –
SCM
2
Soleus Capital Management
Connecticut
$1.5M – – –
ACM
3
Aisling Capital Management
New York
$995K – – –
Vanguard Group
4
Vanguard Group
Pennsylvania
$648K – – –
SCM
5
Stonepine Capital Management
Oregon
$615K -$253K -101,422 -22%
WIA
6
Wealthedge Investment Advisors
New York
$207K +$201K +80,472 +289%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$184K +$13.8K +5,516 +6%
Millennium Management
8
Millennium Management
New York
$113K -$31.6K -12,669 -18%
Envestnet Asset Management
9
Envestnet Asset Management
Illinois
$113K +$31.1K +12,495 +27%
MPM
10
Meritage Portfolio Management
Kansas
$87.9K – – –
Corient Private Wealth
11
Corient Private Wealth
Florida
$72.6K – – –
AI
12
Atria Investments
North Carolina
$71.2K +$8.11K +3,252 +10%
Renaissance Technologies
13
Renaissance Technologies
New York
$67.6K -$19.4K -7,784 -18%
PAM
14
PVG Asset Management
Colorado
$58K +$75.7K +30,385 New
Cetera Investment Advisers
15
Cetera Investment Advisers
Illinois
$52.2K +$26.1K +10,467 +62%
Cambridge Investment Research Advisors
16
Cambridge Investment Research Advisors
Iowa
$45K +$58.7K +23,539 New
JGC
17
J. Goldman & Co
New York
$36.1K – – –
1WA
18
180 Wealth Advisors
Washington
$31.3K +$40.9K +16,400 New
BlackRock
19
BlackRock
New York
$29.4K -$1.35K -541 -3%
TW
20
TritonPoint Wealth
Maryland
$28.9K – – –
First Manhattan
21
First Manhattan
New York
$25.3K +$33K +13,226 New
Bank of America
22
Bank of America
North Carolina
$17.2K +$10 +4 +0%
TRCT
23
Tower Research Capital (TRC)
New York
$5.7K +$4.38K +1,758 +144%
Osaic Holdings
24
Osaic Holdings
Arizona
$5.38K +$4.61K +1,851 +191%
Morgan Stanley
25
Morgan Stanley
New York
$1.64K – – –
1
2

CALC Hedge Fund Activity: Q1 2025 in Review

30 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in CalciMedica (CALC) for Q1 2025, worth a combined $7.49M — down 50% from $15.1M a quarter earlier.

Buyers outnumbered sellers: 4 funds opened new CALC positions and 3 closed out — a net gain of 1 holder — while 8 added to existing stakes and 6 trimmed.

The largest buyer was Wealthedge Investment Advisors, adding an estimated $201K. The largest seller was Alyeska Investment Group, exiting entirely with an estimated $1.32M sold.

  • 30 institutional investors held CalciMedica (CALC) as of Q1 2025, up from 29 in Q4 2024.
  • Funds reported $7.49M of CalciMedica stock for Q1 2025, down 50% quarter-over-quarter.
  • 4 funds opened new CalciMedica positions in Q1 2025 and 3 closed out, a net change of +1 holder.
  • The largest CalciMedica buyer in Q1 2025 was Wealthedge Investment Advisors, an estimated $201K added.
  • The largest CalciMedica seller in Q1 2025 was Alyeska Investment Group, an estimated $1.32M sold.

Based on aggregated 13F filings for Q1 2025.