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CalciMedica
CALC

27 hedge funds and large institutions have $593K invested in CalciMedica in 2026 Q1 according to their latest regulatory filings, with 11 funds opening new positions, 4 increasing their positions, 5 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

13% less funds holding

Funds holding: 31 → 27 (-4)

15% less first-time investments, than exits

New positions opened: 11 | Existing positions closed: 13

18.56% less ownership

Funds ownership: 25.53% → 6.97% (-19%)

20% less repeat investments, than reductions

Existing positions increased: 4 | Existing positions reduced: 5

98% less capital invested

Capital invested by funds: $24.2M → $593K (-$23.7M)

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders
27
Holders Change
-4
Holders Change %
-12.9%
% of All Funds
0.33%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
11
Increased
4
Reduced
5
Closed
13
Calls
$10K
Puts
–
Net Calls
+$10K
Net Calls Change
+$10K

Top Buyers

Rank Fund Capital Flow
1
Jane Street
Jane Street
New York
+$323K
2
1WA
180 Wealth Advisors
Washington
+$192K
3
Cambridge Investment Research Advisors
Cambridge Investment Research Advisors
Iowa
+$122K
4
Renaissance Technologies
Renaissance Technologies
New York
+$80.7K
5
HF
HRT Financial
New York
+$80.6K

Top Sellers

Rank Fund Capital Flow
1
DM
Deerfield Management
New York
-$8.57M
2
SCM
Soleus Capital Management
Connecticut
-$4.51M
3
ACM
Aisling Capital Management
New York
-$3.43M
4
BFM
Boothbay Fund Management
New York
-$506K
5
Envestnet Asset Management
Envestnet Asset Management
Illinois
-$416K
Name Holding Trade Value Shares
Change 		Change in
Stake
Wells Fargo
26
Wells Fargo
California
$5 – – –
BNP Paribas Financial Markets
27
BNP Paribas Financial Markets
France
$2 -$32 -16 -84%
DM
28
Deerfield Management
New York
– -$8.57M -1,300,000 Closed
SCM
29
Soleus Capital Management
Connecticut
– -$4.51M -683,904 Closed
ACM
30
Aisling Capital Management
New York
– -$3.43M -521,114 Closed
BFM
31
Boothbay Fund Management
New York
– -$506K -76,855 Closed
Envestnet Asset Management
32
Envestnet Asset Management
Illinois
– -$416K -63,186 Closed
PAM
33
PVG Asset Management
Colorado
– -$302K -45,830 Closed
SF
34
Summit Financial
New Jersey
– -$234K -35,484 Closed
AI
35
Atria Investments
North Carolina
– -$190K -28,781 Closed
TGY2IT
36
Timothy G. Youngquist 2020 Irrevocable Trust
Florida
– -$157K -23,753 Closed
Cetera Investment Advisers
37
Cetera Investment Advisers
Illinois
– -$147K -22,290 Closed
JGC
38
J. Goldman & Co
New York
– -$125K -18,900 Closed
Millennium Management
39
Millennium Management
New York
– -$97.9K -14,855 Closed
Bank of America
40
Bank of America
North Carolina
– -$59.5K -9,027 Closed
1
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CALC Hedge Fund Activity: Q1 2026 in Review

27 of the 8,161 institutional investors tracked by Wall St. Rank reported a position in CalciMedica (CALC) for Q1 2026, worth a combined $593K — down 98% from $24.2M a quarter earlier.

Sellers outnumbered buyers: 13 funds closed out of CALC and 11 opened new positions — a net loss of 2 holders — while 5 trimmed existing stakes and 4 added.

The largest buyer was Jane Street, adding an estimated $323K. The largest seller was Deerfield Management, exiting entirely with an estimated $8.57M sold.

  • 27 institutional investors held CalciMedica (CALC) as of Q1 2026, down from 31 in Q4 2025.
  • Funds reported $593K of CalciMedica stock for Q1 2026, down 98% quarter-over-quarter.
  • 11 funds opened new CalciMedica positions in Q1 2026 and 13 closed out, a net change of -2 holders.
  • The largest CalciMedica buyer in Q1 2026 was Jane Street, an estimated $323K added.
  • The largest CalciMedica seller in Q1 2026 was Deerfield Management, an estimated $8.57M sold.

Based on aggregated 13F filings for Q1 2026.