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BCYC

Bicycle Therapeutics

98 hedge funds and large institutions have $174M invested in Bicycle Therapeutics in 2026 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 43 increasing their positions, 16 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

169% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 16

3.94% less ownership

Funds ownership: 78.46%74.52% (-3.9%)

10% less funds holding

Funds holding: 10998 (-11)

37% less capital invested

Capital invested by funds: $278M → $174M (-$104M)

42% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 26

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

86% less call options, than puts

Call options by funds: $347K | Put options by funds: $2.48M

Holders
98
Holders Change
-11
Holders Change %
-10.09%
% of All Funds
1.21%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
15
Increased
43
Reduced
16
Closed
26
Calls
$347K
Puts
$2.48M
Net Calls
-$2.13M
Net Calls Change
-$3.52M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$50.5M
FIS
2
FCPM III Services
Netherlands
$16.1M
AC
3
Armistice Capital
New York
$15.8M +$926K +162,000 +5%
LFCM
4
Long Focus Capital Management
Puerto Rico
$15.4M +$9.59M +1,677,596 +103%
Acadian Asset Management
5
Acadian Asset Management
Massachusetts
$9.11M +$1.7M +296,767 +18%
SL
6
Siren LLC
Connecticut
$7.24M -$2.58M -451,870 -22%
GP
7
GSK plc
$7.1M
Principal Financial Group
8
Principal Financial Group
Iowa
$5.45M +$151K +26,353 +2%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$4.77M -$820K -143,544 -12%
Renaissance Technologies
10
Renaissance Technologies
New York
$4.54M +$2.36M +412,700 +73%
Morgan Stanley
11
Morgan Stanley
New York
$2.87M +$875K +153,105 +33%
Schroder Investment Management Group
12
Schroder Investment Management Group
United Kingdom
$2.67M +$178K +31,063 +5%
DP
13
Diadema Partners
New Jersey
$2.21M +$2.72M +476,424 New
BC
14
Birchview Capital
Vermont
$2.15M +$5.14K +899 +0.2%
SAM
15
Silvercrest Asset Management
New York
$1.99M -$276K -48,292 -10%
Marshall Wace
16
Marshall Wace
United Kingdom
$1.75M +$1.93M +338,540 +873%
Citadel Advisors
17
Citadel Advisors
Florida
$1.75M +$604K +105,702 +39%
Qube Research & Technologies (QRT)
18
Qube Research & Technologies (QRT)
United Kingdom
$1.43M +$1.76M +308,617 New
Millennium Management
19
Millennium Management
New York
$1.32M -$244K -42,640 -13%
BlackRock
20
BlackRock
New York
$1.29M -$308K -53,897 -16%
MCM
21
Moore Capital Management
New York
$1.28M
RC
22
Rangeley Capital
Connecticut
$1.08M +$573K +100,260 +76%
Jane Street
23
Jane Street
New York
$1.01M +$885K +154,925 +245%
PAI
24
Palo Alto Investors
California
$937K -$110K -19,181 -9%
EP
25
Eversept Partners
New York
$885K +$67.4K +11,800 +7%

BCYC Hedge Fund Activity: Q1 2026 in Review

98 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Bicycle Therapeutics (BCYC) for Q1 2026, worth a combined $174M — down 37% from $278M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of BCYC and 15 opened new positions — a net loss of 11 holders — while 16 trimmed existing stakes and 43 added.

The largest buyer was Long Focus Capital Management, adding an estimated $9.59M. The largest seller was Westfield Capital Management, exiting entirely with an estimated $21.4M sold.

  • 98 institutional investors held Bicycle Therapeutics (BCYC) as of Q1 2026, down from 109 in Q4 2025.
  • Funds reported $174M of Bicycle Therapeutics stock for Q1 2026, down 37% quarter-over-quarter.
  • 15 funds opened new Bicycle Therapeutics positions in Q1 2026 and 26 closed out, a net change of -11 holders.
  • The largest Bicycle Therapeutics buyer in Q1 2026 was Long Focus Capital Management, an estimated $9.59M added.
  • The largest Bicycle Therapeutics seller in Q1 2026 was Westfield Capital Management, an estimated $21.4M sold.

Based on aggregated 13F filings for Q1 2026.