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BCYC

Bicycle Therapeutics

109 hedge funds and large institutions have $278M invested in Bicycle Therapeutics in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 35 increasing their positions, 29 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

146% more call options, than puts

Call options by funds: $2.33M | Put options by funds: $947K

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

100% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 11

21% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 29

10% more funds holding

Funds holding: 99109 (+10)

4.45% more ownership

Funds ownership: 74.01%78.46% (+4.4%)

3% less capital invested

Capital invested by funds: $286M → $278M (-$7.96M)

Holders
109
Holders Change
+10
Holders Change %
+10.1%
% of All Funds
1.33%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
22
Increased
35
Reduced
29
Closed
11
Calls
$2.33M
Puts
$947K
Net Calls
+$1.39M
Net Calls Change
+$1.02M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$77.1M
FIS
2
FCPM III Services
Netherlands
$24.6M +$119K +16,100 +0.5%
AC
3
Armistice Capital
New York
$22.9M +$1.9M +258,000 +9%
Westfield Capital Management
4
Westfield Capital Management
Massachusetts
$21.4M +$468K +63,483 +2%
SL
5
Siren LLC
Connecticut
$14.3M
Acadian Asset Management
6
Acadian Asset Management
Massachusetts
$11.8M +$2.63M +356,702 +27%
LFCM
7
Long Focus Capital Management
Puerto Rico
$11.6M +$1.58M +214,396 +15%
GP
8
GSK plc
$10.8M +$11.3M +1,529,561 New
CS
9
Candriam SCA
Luxembourg
$8.44M +$147K +19,892 +2%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$8.3M -$1.57M -213,007 -15%
Principal Financial Group
11
Principal Financial Group
Iowa
$8.13M -$958 -130 -0%
BNP Paribas Asset Management
12
BNP Paribas Asset Management
France
$4.02M +$4.19M +568,225 New
Renaissance Technologies
13
Renaissance Technologies
New York
$4.01M +$353K +47,900 +9%
Schroder Investment Management Group
14
Schroder Investment Management Group
United Kingdom
$3.98M +$4.31M +584,770 New
SAM
15
Silvercrest Asset Management
New York
$3.38M
Morgan Stanley
16
Morgan Stanley
New York
$3.29M -$2.64M -357,483 -43%
BC
17
Birchview Capital
Vermont
$3.28M +$2.28M +308,700 +200%
BlackRock
18
BlackRock
New York
$2.36M +$372K +50,471 +18%
Millennium Management
19
Millennium Management
New York
$2.31M -$5.37M -728,120 -69%
JFG
20
Jefferies Financial Group
New York
$2.1M -$772K -104,679 -26%
MCM
21
Moore Capital Management
New York
$1.95M +$1.11M +150,000 +120%
Citadel Advisors
22
Citadel Advisors
Florida
$1.92M +$607K +82,356 +44%
PAI
23
Palo Alto Investors
California
$1.57M
PA
24
Pinnacle Associates
New York
$1.35M -$45.3K -6,138 -3%
PIM
25
Platinum Investment Management
Australia
$1.31M

BCYC Hedge Fund Activity: Q4 2025 in Review

109 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Bicycle Therapeutics (BCYC) for Q4 2025, worth a combined $278M — down 2.8% from $286M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new BCYC positions and 11 closed out — a net gain of 11 holders — while 35 added to existing stakes and 29 trimmed.

The largest buyer was Schroder Investment Management Group, opening a new position worth an estimated $4.31M. The largest seller was Millennium Management, cutting an estimated $5.37M.

  • 109 institutional investors held Bicycle Therapeutics (BCYC) as of Q4 2025, up from 99 in Q3 2025.
  • Funds reported $278M of Bicycle Therapeutics stock for Q4 2025, down 2.8% quarter-over-quarter.
  • 22 funds opened new Bicycle Therapeutics positions in Q4 2025 and 11 closed out, a net change of +11 holders.
  • The largest Bicycle Therapeutics buyer in Q4 2025 was Schroder Investment Management Group, an estimated $4.31M added.
  • The largest Bicycle Therapeutics seller in Q4 2025 was Millennium Management, an estimated $5.37M sold.

Based on aggregated 13F filings for Q4 2025.