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BioCryst Pharmaceuticals

273 hedge funds and large institutions have $1.66B invested in BioCryst Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 92 increasing their positions, 101 reducing their positions, and 57 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 13 (+2)

55% more call options, than puts

Call options by funds: $12M | Put options by funds: $7.76M

12% more capital invested

Capital invested by funds: $1.48B → $1.66B (+$182M)

8.36% more ownership

Funds ownership: 92.5%100.86% (+8.4%)

9% less repeat investments, than reductions

Existing positions increased: 92 | Existing positions reduced: 101

5% less funds holding

Funds holding: 286273 (-13)

14% less first-time investments, than exits

New positions opened: 49 | Existing positions closed: 57

Holders
273
Holders Change
-13
Holders Change %
-4.55%
% of All Funds
3.32%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
49
Increased
92
Reduced
101
Closed
57
Calls
$12M
Puts
$7.76M
Net Calls
+$4.27M
Net Calls Change
+$2.39M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$174M +$3.49M +482,494 +2%
BlackRock
2
BlackRock
New York
$165M -$781K -108,085 -0.5%
RCM
3
RA Capital Management
Massachusetts
$123M +$114M +15,827,186 New
DM
4
Deerfield Management
New York
$112M +$15.7M +2,172,000 +18%
State Street
5
State Street
Massachusetts
$86.4M +$9.15M +1,265,773 +13%
KCM
6
Kynam Capital Management
New Jersey
$73.1M -$172K -23,744 -0.3%
Janus Henderson Group
7
Janus Henderson Group
United Kingdom
$57.8M +$52.9M +7,310,745 +7,807%
UBS Group
8
UBS Group
Switzerland
$41.1M -$5.09M -703,823 -12%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$39.4M +$10.7K +1,479 +0%
Two Sigma Investments
10
Two Sigma Investments
New York
$35.2M +$692K +95,688 +2%
Two Sigma Advisers
11
Two Sigma Advisers
New York
$31.9M -$1.1M -151,600 -4%
RPSM
12
Royalty Pharma Sub-Manager
New York
$30M +$27.8M +3,846,154 New
N
13
Nuveen
North Carolina
$28.2M -$39.9K -5,516 -0.2%
Goldman Sachs
14
Goldman Sachs
New York
$25.1M +$3.62M +500,979 +18%
PA
15
Perceptive Advisors
New York
$24.7M +$22.9M +3,162,529 New
GKIM
16
GW&K Investment Management
Massachusetts
$24.7M +$6.96M +963,159 +44%
EP
17
Eversept Partners
New York
$23.3M +$11.7M +1,619,270 +118%
BBA
18
Baker Bros. Advisors
New York
$22M +$20.4M +2,822,727 New
BNP Paribas Financial Markets
19
BNP Paribas Financial Markets
France
$19.8M +$3.24M +448,436 +21%
Fisher Asset Management
20
Fisher Asset Management
Washington
$19.2M -$1.19M -165,129 -6%
VPC
21
Vestal Point Capital
New York
$17.6M +$16.3M +2,250,000 New
Qube Research & Technologies (QRT)
22
Qube Research & Technologies (QRT)
United Kingdom
$16.9M -$1.78M -246,200 -10%
EC
23
Elmind Capital
New York
$16.8M +$15.5M +2,150,000 New
Renaissance Technologies
24
Renaissance Technologies
New York
$16.6M -$84.7K -11,713 -0.5%
Charles Schwab
25
Charles Schwab
California
$15.6M +$76.2K +10,535 +0.5%