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BioCryst Pharmaceuticals
BCRX

Overview Fund Activity

272 hedge funds and large institutions have $1.31B invested in BioCryst Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 110 increasing their positions, 68 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
272
Holders Change
+14
Holders Change %
+5.43%
% of All Funds
3.69%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
41
Increased
110
Reduced
68
Closed
24
Calls
$9.58M
Puts
$4.81M
Net Calls
+$4.78M
Net Calls Change
+$1.17M

Top Buyers

1
Millennium Management
Millennium Management
New York
+$22.7M
2
UBS Group
UBS Group
Switzerland
+$16.2M
3
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$9.55M
4
JAM
Jupiter Asset Management
United Kingdom
+$7.28M
5
PHP
Parkman Healthcare Partners
Connecticut
+$5.88M

Top Sellers

1
ACA
Avoro Capital Advisors
New York
-$23.7M
2
DM
Deerfield Management
New York
-$22.2M
3
RSCM
Rock Springs Capital Management
Maryland
-$18.4M
4
OIM
Oracle Investment Management
Connecticut
-$4.03M
5
WP
Woodline Partners
California
-$3.39M
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$171M +$5.06M +674,083 +3%
Vanguard Group
2
Vanguard Group
Pennsylvania
$162M -$1.73M -230,657 -1%
KCM
3
Kynam Capital Management
New Jersey
$67M -$1.18M -156,845 -2%
ACA
4
Avoro Capital Advisors
New York
$65.3M -$23.7M -3,165,000 -27%
State Street
5
State Street
Massachusetts
$58.6M +$2.36M +314,437 +4%
Alkeon Capital Management
6
Alkeon Capital Management
New York
$54.1M +$901K +120,199 +2%
DM
7
Deerfield Management
New York
$38.9M -$22.2M -2,954,777 -36%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$37.2M +$1.03M +136,902 +3%
RM
9
RP Management
New York
$28.8M – – –
Millennium Management
10
Millennium Management
New York
$28.6M +$22.7M +3,022,769 +383%
Two Sigma Advisers
11
Two Sigma Advisers
New York
$24.2M +$5.41M +720,900 +29%
CP
12
Caligan Partners
New York
$23.3M +$838K +111,737 +4%
Fisher Asset Management
13
Fisher Asset Management
Washington
$22.9M -$979K -130,480 -4%
GKIM
14
GW&K Investment Management
Massachusetts
$21.6M -$425K -56,716 -2%
UBS Group
15
UBS Group
Switzerland
$18M +$16.2M +2,162,834 +900%
NL
16
Nuveen LLC
North Carolina
$17.2M +$17.2M +1,423,646 New
Morgan Stanley
17
Morgan Stanley
New York
$17.2M +$4.74M +631,942 +38%
EP
18
Eversept Partners
New York
$16.3M +$1.44M +192,124 +10%
JAM
19
Jupiter Asset Management
United Kingdom
$16.1M +$7.28M +971,040 +82%
Two Sigma Investments
20
Two Sigma Investments
New York
$15.3M +$2.03M +271,321 +15%
Voloridge Investment Management
21
Voloridge Investment Management
Florida
$15.3M +$3.4M +453,823 +29%
RHJA
22
Rice Hall James & Associates
California
$15.2M -$403K -53,748 -3%
Northern Trust
23
Northern Trust
Illinois
$14.7M -$372K -49,653 -2%
Goldman Sachs
24
Goldman Sachs
New York
$14.5M +$4.81M +640,704 +50%
Charles Schwab
25
Charles Schwab
California
$14.4M -$435K -57,954 -3%
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