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BioCryst Pharmaceuticals

274 hedge funds and large institutions have $1.32B invested in BioCryst Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 109 increasing their positions, 71 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

99% more call options, than puts

Call options by funds: $9.58M | Put options by funds: $4.8M

71% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 24

54% more repeat investments, than reductions

Existing positions increased: 109 | Existing positions reduced: 71

6% more funds holding

Funds holding: 258274 (+16)

2.69% more ownership

Funds ownership: 80.95%83.64% (+2.7%)

4% more capital invested

Capital invested by funds: $1.26B → $1.32B (+$56.6M)

40% less funds holding in top 10

Funds holding in top 10: 53 (-2)

Holders
274
Holders Change
+16
Holders Change %
+6.2%
% of All Funds
3.67%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
41
Increased
109
Reduced
71
Closed
24
Calls
$9.58M
Puts
$4.8M
Net Calls
+$4.78M
Net Calls Change
+$1.17M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$171M +$5.44M +674,083 +3%
Vanguard Group
2
Vanguard Group
Pennsylvania
$162M -$1.86M -230,657 -1%
KCM
3
Kynam Capital Management
New Jersey
$67M -$1.27M -156,845 -2%
ACA
4
Avoro Capital Advisors
New York
$65.3M -$25.5M -3,165,000 -27%
State Street
5
State Street
Massachusetts
$58.6M +$2.54M +314,437 +4%
Alkeon Capital Management
6
Alkeon Capital Management
New York
$54.1M +$970K +120,199 +2%
DM
7
Deerfield Management
New York
$38.9M -$23.8M -2,954,777 -36%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$37.2M +$1.1M +136,902 +3%
RM
9
RP Management
New York
$28.8M
Millennium Management
10
Millennium Management
New York
$28.6M +$24.4M +3,022,769 +383%
Two Sigma Advisers
11
Two Sigma Advisers
New York
$24.2M +$5.81M +720,900 +29%
CP
12
Caligan Partners
New York
$23.3M +$901K +111,737 +4%
Fisher Asset Management
13
Fisher Asset Management
Washington
$22.9M -$1.05M -130,480 -4%
GKIM
14
GW&K Investment Management
Massachusetts
$21.6M -$457K -56,716 -2%
UBS Group
15
UBS Group
Switzerland
$18M +$17.4M +2,162,834 +900%
N
16
Nuveen
North Carolina
$17.2M -$16.1M -1,995,400 -58%
Morgan Stanley
17
Morgan Stanley
New York
$17.2M +$5.1M +631,942 +38%
EP
18
Eversept Partners
New York
$16.3M +$1.55M +192,124 +10%
JAM
19
Jupiter Asset Management
United Kingdom
$16.1M +$7.83M +971,040 +82%
Two Sigma Investments
20
Two Sigma Investments
New York
$15.3M +$2.19M +271,321 +15%
Voloridge Investment Management
21
Voloridge Investment Management
Florida
$15.3M +$3.66M +453,823 +29%
RHJA
22
Rice Hall James & Associates
California
$15.2M -$434K -53,748 -3%
Northern Trust
23
Northern Trust
Illinois
$14.7M -$401K -49,653 -2%
Goldman Sachs
24
Goldman Sachs
New York
$14.5M +$5.17M +640,704 +50%
Charles Schwab
25
Charles Schwab
California
$14.4M -$467K -57,954 -3%

BCRX Hedge Fund Activity: Q1 2025 in Review

274 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in BioCryst Pharmaceuticals (BCRX) for Q1 2025, worth a combined $1.32B — up 4.5% from $1.26B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new BCRX positions and 24 closed out — a net gain of 17 holders — while 109 added to existing stakes and 71 trimmed.

The largest buyer was Millennium Management, adding an estimated $24.4M. The largest seller was Avoro Capital Advisors, cutting an estimated $25.5M.

  • 274 institutional investors held BioCryst Pharmaceuticals (BCRX) as of Q1 2025, up from 258 in Q4 2024.
  • Funds reported $1.32B of BioCryst Pharmaceuticals stock for Q1 2025, up 4.5% quarter-over-quarter.
  • 41 funds opened new BioCryst Pharmaceuticals positions in Q1 2025 and 24 closed out, a net change of +17 holders.
  • The largest BioCryst Pharmaceuticals buyer in Q1 2025 was Millennium Management, an estimated $24.4M added.
  • The largest BioCryst Pharmaceuticals seller in Q1 2025 was Avoro Capital Advisors, an estimated $25.5M sold.

Based on aggregated 13F filings for Q1 2025.