|
1
|
Suvretta Capital Management
New York
|
$290M
|
+$9.26M
|
+363,000
|
+3%
|
|
|
2
|
Frazier Life Sciences Management
Palo Alto,
California
|
$233M
|
–
|
–
|
–
|
|
|
3
|
|
$217M
|
+$2.57M
|
+100,832
|
+1%
|
|
|
4
|
Rubric Capital Management (New York)
New York
|
$195M
|
–
|
–
|
–
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$148M
|
+$20.6M
|
+807,896
|
+15%
|
|
|
6
|
Polar Capital Holdings
London,
United Kingdom
|
$134M
|
+$2.83M
|
+110,771
|
+2%
|
|
|
7
|
Jennison Associates
New York
|
$117M
|
-$45.4M
|
-1,777,236
|
-26%
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$115M
|
+$124M
|
+4,871,536
|
New
|
|
|
9
|
Gilder Gagnon Howe & Co
New York
|
$101M
|
-$3.82M
|
-149,846
|
-3%
|
|
|
10
|
|
$99.4M
|
-$3.1M
|
-121,308
|
-3%
|
|
|
11
|
UBS Group
Zurich,
Switzerland
|
$78.4M
|
+$2.19M
|
+85,792
|
+3%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$71.8M
|
+$7.45M
|
+291,999
|
+11%
|
|
|
13
|
|
$58.8M
|
-$4.77M
|
-186,865
|
-7%
|
|
|
14
|
Marshall Wace
London,
United Kingdom
|
$57.3M
|
+$50.5M
|
+1,977,545
|
+435%
|
|
|
15
|
Franklin Resources
San Mateo,
California
|
$54.1M
|
+$10.2M
|
+397,859
|
+21%
|
|
|
16
|
Driehaus Capital Management
Chicago,
Illinois
|
$52.4M
|
-$8.59M
|
-336,416
|
-13%
|
|
|
17
|
Bank of America
Charlotte,
North Carolina
|
$52.3M
|
+$14M
|
+547,835
|
+33%
|
|
|
18
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$46.1M
|
+$49.9M
|
+1,954,685
|
New
|
|
|
19
|
Janus Henderson Group
London,
|
$43.7M
|
+$625K
|
+24,505
|
+1%
|
|
|
20
|
|
$37.8M
|
+$679K
|
+26,600
|
+2%
|
|
|
21
|
American Century Companies
Kansas City,
Missouri
|
$34.5M
|
-$101K
|
-3,948
|
-0.3%
|
|
|
22
|
Oberweis Asset Management
Lisle,
Illinois
|
$32.2M
|
+$14.2M
|
+557,541
|
+69%
|
|
|
23
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
$31.9M
|
-$274K
|
-10,732
|
-0.8%
|
|
|
24
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$29.3M
|
-$16.8M
|
-658,003
|
-35%
|
|
|
25
|
|
$26M
|
+$16.5M
|
+647,614
|
+142%
|
|
