|
1
|
Frazier Management
Seattle,
Washington
|
$230M
|
-$59.4M
|
-2,108,558
|
-20%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$206M
|
-$2.98M
|
-105,709
|
-1%
|
|
|
3
|
|
$166M
|
–
|
–
|
–
|
|
|
4
|
|
$116M
|
+$1.31M
|
+46,661
|
+1%
|
|
|
5
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$109M
|
–
|
–
|
–
|
|
|
6
|
Polar Capital Holdings
London,
United Kingdom
|
$45.9M
|
+$3.52M
|
+125,000
|
+8%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$40.8M
|
-$994K
|
-35,294
|
-2%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$31.5M
|
+$5.2M
|
+184,500
|
+19%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$25.2M
|
+$7.56M
|
+268,537
|
+41%
|
|
|
10
|
Wells Fargo
San Francisco,
California
|
$24.5M
|
+$602K
|
+21,388
|
+2%
|
|
|
11
|
Point72 Asset Management
Stamford,
Connecticut
|
$24.5M
|
+$12.9M
|
+457,100
|
+104%
|
|
|
12
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$20.7M
|
-$3.39M
|
-120,185
|
-14%
|
|
|
13
|
Omega Fund Management
Boston,
Massachusetts
|
$17M
|
–
|
–
|
–
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$15.7M
|
-$2.18M
|
-77,280
|
-12%
|
|
|
15
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
$15.5M
|
–
|
–
|
–
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$13M
|
+$1.22M
|
+43,209
|
+10%
|
|
|
17
|
Citadel Advisors
Miami,
Florida
|
$12M
|
-$308K
|
-10,944
|
-2%
|
|
|
18
|
Vivo Capital
Palo Alto,
California
|
$11.8M
|
-$8.75M
|
-310,785
|
-42%
|
|
|
19
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$10.8M
|
+$6.37M
|
+226,013
|
+132%
|
|
|
20
|
American Century Companies
Kansas City,
Missouri
|
$10.3M
|
+$23.2K
|
+824
|
+0.2%
|
|
|
21
|
Ameriprise
Minneapolis,
Minnesota
|
$9.69M
|
+$1.06M
|
+37,677
|
+12%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$7.92M
|
+$656K
|
+23,285
|
+9%
|
|
|
23
|
Nuveen
Charlotte,
North Carolina
|
$7.2M
|
+$1.15M
|
+40,838
|
+18%
|
|
|
24
|
|
$6.64M
|
+$530K
|
+18,816
|
+8%
|
|
|
25
|
Altium Capital Management
New York
|
$6.31M
|
+$3.31M
|
+117,352
|
+103%
|
|
