|
1
|
Frazier Management
Seattle,
Washington
|
$314M
|
+$283M
|
+10,542,790
|
New
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$170M
|
+$154M
|
+5,713,343
|
New
|
|
|
3
|
|
$139M
|
+$126M
|
+4,673,850
|
New
|
|
|
4
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$119M
|
+$107M
|
+3,979,292
|
New
|
|
|
5
|
Vivo Capital
Palo Alto,
California
|
$50.3M
|
+$45.3M
|
+1,686,527
|
New
|
|
|
6
|
RA Capital Management
Boston,
Massachusetts
|
$34.7M
|
+$31.3M
|
+1,165,184
|
New
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$29.2M
|
+$26.3M
|
+980,614
|
New
|
|
|
8
|
|
$25.8M
|
+$23.2M
|
+865,309
|
New
|
|
|
9
|
Omega Fund Management
Boston,
Massachusetts
|
$25.2M
|
+$22.7M
|
+844,680
|
New
|
|
|
10
|
Wells Fargo
San Francisco,
California
|
$12.3M
|
+$11.1M
|
+413,771
|
New
|
|
|
11
|
Polar Capital
London,
United Kingdom
|
$11.2M
|
+$10.1M
|
+375,000
|
New
|
|
|
12
|
Ameriprise
Minneapolis,
Minnesota
|
$7.58M
|
+$6.84M
|
+254,439
|
New
|
|
|
13
|
|
$5.95M
|
+$5.36M
|
+199,630
|
New
|
|
|
14
|
Vanguard Group
Malvern,
Pennsylvania
|
$5.23M
|
+$4.71M
|
+175,408
|
New
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$4.99M
|
+$4.5M
|
+167,558
|
New
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$3.23M
|
+$2.91M
|
+108,459
|
New
|
|
|
17
|
AllianceBernstein
Nashville,
Tennessee
|
$2.05M
|
+$1.85M
|
+68,836
|
New
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$1.8M
|
+$1.62M
|
+60,380
|
New
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$1.66M
|
+$1.49M
|
+55,565
|
New
|
|
|
20
|
Laurion Capital Management
New York
|
$1.49M
|
+$1.34M
|
+50,000
|
New
|
|
|
21
|
Marshall Wace North America
New York
|
$1.23M
|
+$1.11M
|
+41,315
|
New
|
|
|
22
|
Nuveen
Charlotte,
North Carolina
|
$1.16M
|
+$1.05M
|
+38,896
|
New
|
|
|
23
|
Bank of New York Mellon
New York
|
$718K
|
+$647K
|
+24,084
|
New
|
|
|
24
|
CAAS Capital Management
New York
|
$668K
|
+$602K
|
+22,413
|
New
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$657K
|
+$592K
|
+22,021
|
New
|
|
