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508 hedge funds and large institutions have $25B invested in argenx in 2025 Q4 according to their latest regulatory filings, with 99 funds opening new positions, 175 increasing their positions, 167 reducing their positions, and 53 closing their positions.

New
Increased
Maintained
Reduced
Closed

120% more call options, than puts

Call options by funds: $364M | Put options by funds: $165M

87% more first-time investments, than exits

New positions opened: 99 | Existing positions closed: 53

11% more capital invested

Capital invested by funds: $22.5B → $25B (+$2.49B)

8% more funds holding

Funds holding: 469508 (+39)

5% more repeat investments, than reductions

Existing positions increased: 175 | Existing positions reduced: 167

0% more funds holding in top 10

Funds holding in top 10: 1414 (0)

1.55% less ownership

Funds ownership: 49.87%48.32% (-1.6%)

Holders
508
Holders Change
+39
Holders Change %
+8.32%
% of All Funds
6.15%
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.17%
New
99
Increased
175
Reduced
167
Closed
53
Calls
$364M
Puts
$165M
Net Calls
+$199M
Net Calls Change
-$90.1M

ARGX Hedge Fund Activity: Q4 2025 in Review

508 of the 8,264 institutional investors tracked by Wall St. Rank reported a position in argenx (ARGX) for Q4 2025, worth a combined $25B — up 11% from $22.5B a quarter earlier.

Buyers outnumbered sellers: 99 funds opened new ARGX positions and 53 closed out — a net gain of 46 holders — while 175 added to existing stakes and 167 trimmed.

The largest buyer was Sands Capital Management, adding an estimated $291M. The largest seller was Artisan Partners, cutting an estimated $368M.

  • 508 institutional investors held argenx (ARGX) as of Q4 2025, up from 469 in Q3 2025.
  • Funds reported $25B of argenx stock for Q4 2025, up 11% quarter-over-quarter.
  • 99 funds opened new argenx positions in Q4 2025 and 53 closed out, a net change of +46 holders.
  • The largest argenx buyer in Q4 2025 was Sands Capital Management, an estimated $291M added.
  • The largest argenx seller in Q4 2025 was Artisan Partners, an estimated $368M sold.

Based on aggregated 13F filings for Q4 2025.