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438 hedge funds and large institutions have $17.7B invested in argenx in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 177 increasing their positions, 145 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

126% more call options, than puts

Call options by funds: $270M | Put options by funds: $120M

22% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 145

2% less funds holding

Funds holding: 447438 (-9)

2.3% less ownership

Funds ownership: 54.9%52.6% (-2.3%)

6% less funds holding in top 10

Funds holding in top 10: 1817 (-1)

10% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 60

10% less capital invested

Capital invested by funds: $19.7B → $17.7B (-$2.03B)

Holders
438
Holders Change
-9
Holders Change %
-2.01%
% of All Funds
5.77%
Holding in Top 10
17
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-5.56%
% of All Funds
0.22%
New
54
Increased
177
Reduced
145
Closed
60
Calls
$270M
Puts
$120M
Net Calls
+$151M
Net Calls Change
+$5.36M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$2.99B -$139M -239,699 -4%
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$2.75B -$235M -404,610 -8%
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$1.41B +$245M +422,316 +20%
Artisan Partners
4
Artisan Partners
Wisconsin
$1.3B -$253M -436,114 -16%
Capital World Investors
5
Capital World Investors
California
$1.08B +$7.6M +13,090 +0.7%
ACA
6
Avoro Capital Advisors
New York
$648M -$34.9M -60,177 -5%
Citadel Advisors
7
Citadel Advisors
Florida
$477M +$182M +314,031 +57%
ClearBridge Investments
8
ClearBridge Investments
New York
$426M +$63M +108,498 +16%
RI
9
RTW Investments
New York
$371M
BG
10
Bellevue Group
Switzerland
$315M -$4.55M -7,835 -1%
BlackRock
11
BlackRock
New York
$303M -$273M -471,179 -46%
Millennium Management
12
Millennium Management
New York
$237M +$93.6M +161,240 +60%
Morgan Stanley
13
Morgan Stanley
New York
$237M -$260M -447,859 -51%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$223M -$505K -871 -0.2%
Bank of America
15
Bank of America
North Carolina
$185M -$2.32M -3,995 -1%
SEI Investments
16
SEI Investments
Pennsylvania
$174M -$25.9M -44,601 -12%
Adage Capital Partners
17
Adage Capital Partners
Massachusetts
$164M +$92M +158,476 +114%
Franklin Resources
18
Franklin Resources
California
$154M +$82.8M +142,606 +104%
Jennison Associates
19
Jennison Associates
New York
$146M +$8.81M +15,186 +6%
Invesco
20
Invesco
Georgia
$134M -$80.7M -138,995 -36%
O
21
OrbiMed
New York
$115M +$754K +1,300 +0.6%
American Century Companies
22
American Century Companies
Missouri
$114M +$33.1M +57,054 +38%
Pictet Asset Management
23
Pictet Asset Management
Switzerland
$109M -$18.7M -32,155 -14%
B
24
Braidwell
Connecticut
$107M +$19.5M +33,642 +21%
Allspring Global Investments
25
Allspring Global Investments
North Carolina
$100M +$4.95M +8,537 +5%

ARGX Hedge Fund Activity: Q2 2025 in Review

438 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in argenx (ARGX) for Q2 2025, worth a combined $17.7B — down 10% from $19.7B a quarter earlier.

Sellers outnumbered buyers: 60 funds closed out of ARGX and 54 opened new positions — a net loss of 6 holders — while 145 trimmed existing stakes and 177 added.

The largest buyer was Janus Henderson Group, adding an estimated $245M. The largest seller was BlackRock, cutting an estimated $273M.

  • 438 institutional investors held argenx (ARGX) as of Q2 2025, down from 447 in Q1 2025.
  • Funds reported $17.7B of argenx stock for Q2 2025, down 10% quarter-over-quarter.
  • 54 funds opened new argenx positions in Q2 2025 and 60 closed out, a net change of -6 holders.
  • The largest argenx buyer in Q2 2025 was Janus Henderson Group, an estimated $245M added.
  • The largest argenx seller in Q2 2025 was BlackRock, an estimated $273M sold.

Based on aggregated 13F filings for Q2 2025.