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468 hedge funds and large institutions have $22.5B invested in argenx in 2025 Q3 according to their latest regulatory filings, with 91 funds opening new positions, 177 increasing their positions, 136 reducing their positions, and 57 closing their positions.

New
Increased
Maintained
Reduced
Closed

114% more call options, than puts

Call options by funds: $542M | Put options by funds: $253M

60% more first-time investments, than exits

New positions opened: 91 | Existing positions closed: 57

30% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 136

27% more capital invested

Capital invested by funds: $17.7B → $22.5B (+$4.81B)

7% more funds holding

Funds holding: 437468 (+31)

2.73% less ownership

Funds ownership: 52.6%49.87% (-2.7%)

18% less funds holding in top 10

Funds holding in top 10: 1714 (-3)

Holders
468
Holders Change
+31
Holders Change %
+7.09%
% of All Funds
6.14%
Holding in Top 10
14
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-17.65%
% of All Funds
0.18%
New
91
Increased
177
Reduced
136
Closed
57
Calls
$542M
Puts
$253M
Net Calls
+$289M
Net Calls Change
+$139M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$4.2B +$177M +268,838 +5%
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$2.69B -$883M -1,339,567 -27%
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$1.9B +$6.5M +9,852 +0.4%
Artisan Partners
4
Artisan Partners
Wisconsin
$1.61B -$108M -163,266 -7%
Capital World Investors
5
Capital World Investors
California
$1.45B +$5.55M +8,422 +0.4%
ACA
6
Avoro Capital Advisors
New York
$730M -$122M -185,000 -16%
ClearBridge Investments
7
ClearBridge Investments
New York
$558M -$10.6M -16,004 -2%
Wellington Management Group
8
Wellington Management Group
Massachusetts
$538M +$214M +324,653 +80%
Citadel Advisors
9
Citadel Advisors
Florida
$526M -$100M -152,411 -18%
RI
10
RTW Investments
New York
$497M
BG
11
Bellevue Group
Switzerland
$403M -$16.3M -24,711 -4%
BlackRock
12
BlackRock
New York
$386M -$17.4M -26,345 -5%
Morgan Stanley
13
Morgan Stanley
New York
$321M +$3.83M +5,815 +1%
Millennium Management
14
Millennium Management
New York
$256M -$54.3M -82,326 -19%
Bank of America
15
Bank of America
North Carolina
$253M +$4.13M +6,259 +2%
SEI Investments
16
SEI Investments
Pennsylvania
$230M -$2.72M -4,131 -1%
Two Sigma Investments
17
Two Sigma Investments
New York
$217M +$165M +250,278 +570%
Franklin Resources
18
Franklin Resources
California
$190M -$14.2M -21,529 -8%
Jennison Associates
19
Jennison Associates
New York
$177M -$16.1M -24,419 -9%
American Century Companies
20
American Century Companies
Missouri
$169M +$15.7M +23,864 +12%
Allspring Global Investments
21
Allspring Global Investments
North Carolina
$162M +$17.4M +26,343 +14%
Lord, Abbett & Co
22
Lord, Abbett & Co
New Jersey
$145M +$63.2M +95,798 +95%
Goldman Sachs
23
Goldman Sachs
New York
$142M +$33.6M +50,963 +36%
Fiera Capital (Canada)
24
Fiera Capital (Canada)
Quebec, Canada
$131M +$12.6M +19,180 +12%
Alkeon Capital Management
25
Alkeon Capital Management
New York
$129M +$65.9M +100,000 +133%

ARGX Hedge Fund Activity: Q3 2025 in Review

468 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in argenx (ARGX) for Q3 2025, worth a combined $22.5B — up 27% from $17.7B a quarter earlier.

Buyers outnumbered sellers: 91 funds opened new ARGX positions and 57 closed out — a net gain of 34 holders — while 177 added to existing stakes and 136 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $214M. The largest seller was T. Rowe Price Associates, cutting an estimated $883M.

  • 468 institutional investors held argenx (ARGX) as of Q3 2025, up from 437 in Q2 2025.
  • Funds reported $22.5B of argenx stock for Q3 2025, up 27% quarter-over-quarter.
  • 91 funds opened new argenx positions in Q3 2025 and 57 closed out, a net change of +34 holders.
  • The largest argenx buyer in Q3 2025 was Wellington Management Group, an estimated $214M added.
  • The largest argenx seller in Q3 2025 was T. Rowe Price Associates, an estimated $883M sold.

Based on aggregated 13F filings for Q3 2025.