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438 hedge funds and large institutions have $17.7B invested in argenx in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 177 increasing their positions, 145 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

126% more call options, than puts

Call options by funds: $270M | Put options by funds: $120M

22% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 145

2% less funds holding

Funds holding: 447438 (-9)

2.3% less ownership

Funds ownership: 54.9%52.6% (-2.3%)

6% less funds holding in top 10

Funds holding in top 10: 1817 (-1)

10% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 60

10% less capital invested

Capital invested by funds: $19.7B → $17.7B (-$2.03B)

Holders
438
Holders Change
-9
Holders Change %
-2.01%
% of All Funds
5.77%
Holding in Top 10
17
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-5.56%
% of All Funds
0.22%
New
54
Increased
177
Reduced
145
Closed
60
Calls
$270M
Puts
$120M
Net Calls
+$151M
Net Calls Change
+$5.36M
Name Holding Trade Value Shares
Change
Change in
Stake
UOC
201
UBS O'Connor
Illinois
$1.21M +$1.27M +2,191 New
WSFS
202
Wilmington Savings Fund Society
Delaware
$1.16M +$105K +181 +9%
Osaic Holdings
203
Osaic Holdings
Arizona
$1.09M -$68.5K -118 -6%
PAS
204
Park Avenue Securities
New York
$1.07M +$76.6K +132 +7%
Sumitomo Mitsui Trust Group
205
Sumitomo Mitsui Trust Group
Japan
$1.07M +$239K +412 +27%
SCA
206
Snowden Capital Advisors
New York
$1.05M +$32.5K +56 +3%
Kovitz Investment Group Partners
207
Kovitz Investment Group Partners
Illinois
$1.03M +$304K +523 +39%
PAMP
208
Polar Asset Management Partners
Ontario, Canada
$1.02M -$2.08M -3,578 -66%
Alyeska Investment Group
209
Alyeska Investment Group
Illinois
$1.01M +$1.07M +1,836 New
SFA
210
Sequoia Financial Advisors
Ohio
$1.01M +$2.32K +4 +0.2%
PNC Financial Services Group
211
PNC Financial Services Group
Pennsylvania
$981K +$133K +230 +15%
ACM
212
ADAR1 Capital Management
Texas
$970K +$673K +1,159 +193%
ORI
213
Oak Ridge Investments
Illinois
$944K -$1.16K -2 -0.1%
S
214
SignatureFD
Georgia
$925K -$4.64K -8 -0.5%
Daiwa Securities Group
215
Daiwa Securities Group
Japan
$923K +$270K +465 +38%
KeyBank National Association
216
KeyBank National Association
Ohio
$911K -$11K -19 -1%
Royal London Asset Management
217
Royal London Asset Management
United Kingdom
$877K -$139K -240 -13%
MGWM
218
Marks Group Wealth Management
Minnesota
$840K +$174K +299 +24%
CG
219
Cynosure Group
Utah
$836K +$225K +388 +34%
Corient Private Wealth
220
Corient Private Wealth
Florida
$833K +$45.8K +79 +6%
WAS
221
WESPAC Advisors SoCal
California
$824K +$868K +1,495 New
SAM
222
Simplify Asset Management
Nevada
$809K -$88.2K -152 -9%
MMEA
223
Main Management ETF Advisors
California
$808K +$13.9K +24 +2%
CFO
224
Callan Family Office
Pennsylvania
$800K +$633K +1,090 +301%
KIA
225
Knollwood Investment Advisory
Maryland
$771K

ARGX Hedge Fund Activity: Q2 2025 in Review

438 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in argenx (ARGX) for Q2 2025, worth a combined $17.7B — down 10% from $19.7B a quarter earlier.

Sellers outnumbered buyers: 60 funds closed out of ARGX and 54 opened new positions — a net loss of 6 holders — while 145 trimmed existing stakes and 177 added.

The largest buyer was Janus Henderson Group, adding an estimated $245M. The largest seller was BlackRock, cutting an estimated $273M.

  • 438 institutional investors held argenx (ARGX) as of Q2 2025, down from 447 in Q1 2025.
  • Funds reported $17.7B of argenx stock for Q2 2025, down 10% quarter-over-quarter.
  • 54 funds opened new argenx positions in Q2 2025 and 60 closed out, a net change of -6 holders.
  • The largest argenx buyer in Q2 2025 was Janus Henderson Group, an estimated $245M added.
  • The largest argenx seller in Q2 2025 was BlackRock, an estimated $273M sold.

Based on aggregated 13F filings for Q2 2025.