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438 hedge funds and large institutions have $17.7B invested in argenx in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 177 increasing their positions, 145 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

126% more call options, than puts

Call options by funds: $270M | Put options by funds: $120M

22% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 145

2% less funds holding

Funds holding: 447438 (-9)

2.3% less ownership

Funds ownership: 54.9%52.6% (-2.3%)

6% less funds holding in top 10

Funds holding in top 10: 1817 (-1)

10% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 60

10% less capital invested

Capital invested by funds: $19.7B → $17.7B (-$2.03B)

Holders
438
Holders Change
-9
Holders Change %
-2.01%
% of All Funds
5.77%
Holding in Top 10
17
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-5.56%
% of All Funds
0.22%
New
54
Increased
177
Reduced
145
Closed
60
Calls
$270M
Puts
$120M
Net Calls
+$151M
Net Calls Change
+$5.36M
Name Holding Trade Value Shares
Change
Change in
Stake
AC
51
Armistice Capital
New York
$44.1M -$10.4M -18,000 -18%
AGP
52
Artia Global Partners
Florida
$43.2M +$38.9M +67,000 +592%
EHI
53
Eagle Health Investments
Connecticut
$42.7M +$1.42M +2,440 +3%
PI
54
PineBridge Investments
New York
$42.3M +$2.07M +3,566 +5%
PI
55
PGGM Investments
Netherlands
$42.3M +$16.2M +27,900 +57%
Alkeon Capital Management
56
Alkeon Capital Management
New York
$41.3M
Raymond James Financial
57
Raymond James Financial
Florida
$40M +$3.32M +5,715 +9%
Aberdeen Group
58
Aberdeen Group
United Kingdom
$38.7M +$9.11M +15,703 +29%
UBS Group
59
UBS Group
Switzerland
$37.6M -$19.7M -33,863 -33%
Hudson Bay Capital Management
60
Hudson Bay Capital Management
Connecticut
$37.4M +$39.4M +67,923 New
BNP Paribas Financial Markets
61
BNP Paribas Financial Markets
France
$36.8M -$38.6M -66,564 -50%
New York State Common Retirement Fund
62
New York State Common Retirement Fund
New York
$35.3M -$85.9K -148 -0.2%
Manulife (Manufacturers Life Insurance)
63
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$34.9M +$2.06M +3,549 +6%
Northern Trust
64
Northern Trust
Illinois
$34.7M +$6.1M +10,506 +20%
First Trust Advisors
65
First Trust Advisors
Illinois
$32.4M -$1.53M -2,630 -4%
Qube Research & Technologies (QRT)
66
Qube Research & Technologies (QRT)
United Kingdom
$32.1M -$11.4M -19,711 -25%
Wells Fargo
67
Wells Fargo
California
$30.5M -$6.9M -11,882 -18%
AllianceBernstein
68
AllianceBernstein
Tennessee
$29.7M +$30.4M +52,428 +3,726%
TLP
69
Tri Locum Partners
New York
$26.3M +$17.4M +29,949 +168%
MCM
70
Moore Capital Management
New York
$25.9M +$12.8M +22,000 +88%
CS
71
Candriam SCA
Luxembourg
$25.1M +$2.49M +4,287 +10%
FTM
72
First Turn Management
California
$24.2M +$1.19M +2,042 +5%
Two Sigma Investments
73
Two Sigma Investments
New York
$24.2M -$17.4M -30,066 -41%
SCM
74
Soleus Capital Management
Connecticut
$23.6M +$8.09M +13,936 +48%
VanEck Associates
75
VanEck Associates
New York
$22.9M -$1.65M -2,842 -6%

ARGX Hedge Fund Activity: Q2 2025 in Review

438 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in argenx (ARGX) for Q2 2025, worth a combined $17.7B — down 10% from $19.7B a quarter earlier.

Sellers outnumbered buyers: 60 funds closed out of ARGX and 54 opened new positions — a net loss of 6 holders — while 145 trimmed existing stakes and 177 added.

The largest buyer was Janus Henderson Group, adding an estimated $245M. The largest seller was BlackRock, cutting an estimated $273M.

  • 438 institutional investors held argenx (ARGX) as of Q2 2025, down from 447 in Q1 2025.
  • Funds reported $17.7B of argenx stock for Q2 2025, down 10% quarter-over-quarter.
  • 54 funds opened new argenx positions in Q2 2025 and 60 closed out, a net change of -6 holders.
  • The largest argenx buyer in Q2 2025 was Janus Henderson Group, an estimated $245M added.
  • The largest argenx seller in Q2 2025 was BlackRock, an estimated $273M sold.

Based on aggregated 13F filings for Q2 2025.