Applied Therapeutics
APLT
APLT was delisted on the 2nd of February, 2026.
70 hedge funds and large institutions have $57.2M invested in Applied Therapeutics in 2025 Q3 according to their latest regulatory filings, with 11 funds opening new positions, 15 increasing their positions, 26 reducing their positions, and 16 closing their positions.
223% more call options, than puts
Call options by funds: $682K | Put options by funds: $211K
109% more capital invested
Capital invested by funds: $27.4M → $57.2M (+$29.8M)
3.6% more ownership
Funds ownership: 62.2% → 65.8% (+3.6%)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
7% less funds holding
Funds holding: 75 → 70 (-5)
31% less first-time investments, than exits
New positions opened: 11 | Existing positions closed: 16
42% less repeat investments, than reductions
Existing positions increased: 15 | Existing positions reduced: 26
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PNC Financial Services Group
Pittsburgh,
Pennsylvania
|
+$1.37M |
| 2 |
VPC
Vestal Point Capital
New York
|
+$1.3M |
| 3 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
+$1.28M |
| 4 |
UBS Group
Zurich,
Switzerland
|
+$506K |
| 5 |
Adage Capital Partners
Boston,
Massachusetts
|
+$471K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
TCM
Tang Capital Management
San Diego,
California
|
-$755K |
| 2 |
BlackRock
New York
|
-$648K |
| 3 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
-$309K |
| 4 |
Goldman Sachs
New York
|
-$271K |
| 5 |
Citadel Advisors
Miami,
Florida
|
-$223K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
JG
76
Jain Global
New York
| – | -$26.4K | -84,890 | Closed |
|
|
CF
77
Cantor Fitzgerald
New York
| – | -$7.78K | -25,000 | Closed |
|
|
IC
78
IEQ Capital
Foster City,
California
| – | -$5.06K | -16,251 | Closed |
|
|
BBA
79
Baader Bank Aktiengesellschaft
Unterschleissheim,
Germany
| – | -$2.63K | -13,700 | Closed |
|
|
ECM
80
ExodusPoint Capital Management
New York
| – | -$3K | -10,457 | Closed |
|
|
JF
81
Jump Financial
Chicago,
Illinois
| – | -$3.15K | -10,122 | Closed |
|
82
Carson Wealth (CWM LLC)
Omaha,
Nebraska
| – | -$2.44K | -5,176 | -93% |
|
83
Wells Fargo
San Francisco,
California
| – | -$776 | -2,494 | Closed |
|
84
Nisa Investment Advisors
St. Louis,
Missouri
| – | -$178 | -573 | Closed |
|
|
EP
85
Essential Partners
Rancho Santa Fe,
California
| – | -$70 | -225 | Closed |
|
|
TWD
86
True Wealth Design
Akron,
Ohio
| – | -$19 | -59 | Closed |
|
APLT Hedge Fund Activity: Q3 2025 in Review
70 of the 7,624 institutional investors tracked by Wall St. Rank reported a position in Applied Therapeutics (APLT) for Q3 2025, worth a combined $57.2M — up 109% from $27.4M a quarter earlier.
Sellers outnumbered buyers: 16 funds closed out of APLT and 11 opened new positions — a net loss of 5 holders — while 26 trimmed existing stakes and 15 added.
The largest buyer was PNC Financial Services Group, opening a new position worth an estimated $1.37M. The largest seller was Tang Capital Management, exiting entirely with an estimated $755K sold.
- 70 institutional investors held Applied Therapeutics (APLT) as of Q3 2025, down from 75 in Q2 2025.
- Funds reported $57.2M of Applied Therapeutics stock for Q3 2025, up 109% quarter-over-quarter.
- 11 funds opened new Applied Therapeutics positions in Q3 2025 and 16 closed out, a net change of -5 holders.
- The largest Applied Therapeutics buyer in Q3 2025 was PNC Financial Services Group, an estimated $1.37M added.
- The largest Applied Therapeutics seller in Q3 2025 was Tang Capital Management, an estimated $755K sold.
Based on aggregated 13F filings for Q3 2025.