Applied Therapeutics
APLT
APLT was delisted on the 2nd of February, 2026.
69 hedge funds and large institutions have $133M invested in Applied Therapeutics in 2021 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 29 increasing their positions, 16 reducing their positions, and 11 closing their positions.
119% more call options, than puts
Call options by funds: $1.1M | Put options by funds: $503K
81% more repeat investments, than reductions
Existing positions increased: 29 | Existing positions reduced: 16
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
0.8% less ownership
Funds ownership: 57.71% → 56.91% (-0.8%)
9% less first-time investments, than exits
New positions opened: 10 | Existing positions closed: 11
1% less funds holding
Funds holding: 70 → 69 (-1)
47% less capital invested
Capital invested by funds: $251M → $133M (-$117M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Franklin Resources
San Mateo,
California
|
+$3.82M |
| 2 |
KPW
Kore Private Wealth
New York
|
+$1.64M |
| 3 |
Point72 Asset Management
Stamford,
Connecticut
|
+$1.3M |
| 4 |
Millennium Management
New York
|
+$767K |
| 5 |
O
OrbiMed
New York
|
+$739K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Alkeon Capital Management
New York
|
-$10.6M |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
-$2.19M |
| 3 |
VOYA Investment Management
Atlanta,
Georgia
|
-$1.88M |
| 4 |
DCM
Driehaus Capital Management
Chicago,
Illinois
|
-$1.61M |
| 5 |
ACM
ACT Capital Management
Wayne,
Pennsylvania
|
-$230K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
QT
76
Quantbot Technologies
New York
| – | -$8K | -500 | Closed |
|
77
US Bancorp
Minneapolis,
Minnesota
| – | -$2K | -103 | Closed |
|
|
PA
78
Parallel Advisors
San Francisco,
California
| – | -$1K | -90 | Closed |
|
79
Osaic Holdings
Scottsdale,
Arizona
| – | -$657 | -50 | -50% |
|
APLT Hedge Fund Activity: Q4 2021 in Review
69 of the 6,499 institutional investors tracked by Wall St. Rank reported a position in Applied Therapeutics (APLT) for Q4 2021, worth a combined $133M — down 47% from $251M a quarter earlier.
Sellers outnumbered buyers: 11 funds closed out of APLT and 10 opened new positions — a net loss of 1 holder — while 16 trimmed existing stakes and 29 added.
The largest buyer was Franklin Resources, adding an estimated $3.82M. The largest seller was Alkeon Capital Management, exiting entirely with an estimated $10.6M sold.
- 69 institutional investors held Applied Therapeutics (APLT) as of Q4 2021, down from 70 in Q3 2021.
- Funds reported $133M of Applied Therapeutics stock for Q4 2021, down 47% quarter-over-quarter.
- 10 funds opened new Applied Therapeutics positions in Q4 2021 and 11 closed out, a net change of -1 holder.
- The largest Applied Therapeutics buyer in Q4 2021 was Franklin Resources, an estimated $3.82M added.
- The largest Applied Therapeutics seller in Q4 2021 was Alkeon Capital Management, an estimated $10.6M sold.
Based on aggregated 13F filings for Q4 2021.