APLS icon

Apellis Pharmaceuticals
APLS

Overview Fund Activity

243 hedge funds and large institutions have $2.26B invested in Apellis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 43 funds opening new positions, 106 increasing their positions, 68 reducing their positions, and 49 closing their positions.

Holders
243
Holders Change
-11
Holders Change %
-4.33%
% of All Funds
3.26%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
43
Increased
106
Reduced
68
Closed
49
Calls
$47.3M
Puts
$9.73M
Net Calls
+$37.5M
Net Calls Change
+$30.8M

Top Buyers

1
Marshall Wace
1
Marshall Wace
United Kingdom
$46.8M
2
Norges Bank
2
Norges Bank
Norway
$41M
3
DTC
3
Deep Track Capital
Connecticut
$121M
4
AQR Capital Management
4
AQR Capital Management
Connecticut
$103M
5
UBS Group
5
UBS Group
Switzerland
$82M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$155M
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$334K
3
Man Group
3
Man Group
United Kingdom
$0
4
OCA
4
Octagon Capital Advisors
New York
$15.6M
5
National Bank of Canada
5
National Bank of Canada
Quebec, Canada
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Two Sigma Advisers
51
Two Sigma Advisers
New York
$4.45M 256,800 +65,000 +34%
D.E. Shaw & Co
52
D.E. Shaw & Co
New York
$4.35M 251,069 +251,069 New
Jane Street
53
Jane Street
New York
$4.26M 246,199 -9,893 -4%
Bank of New York Mellon
54
Bank of New York Mellon
New York
$4.21M 243,327 -85,846 -26%
JPMorgan Chase & Co
55
JPMorgan Chase & Co
New York
$4.06M 234,801 -188,999 -45%
CM
56
Caption Management
Oklahoma
$4M 230,888 +218,888 +1,824%
EP
57
Edgestream Partners
New Jersey
$3.78M 218,392 -22,895 -9%
Goldman Sachs
58
Goldman Sachs
New York
$3.74M 215,999 -91,710 -30%
FT
59
Fiduciary Trust
Massachusetts
$3.51M 202,536 -800 -0.4%
Millennium Management
60
Millennium Management
New York
$3.5M 202,452 -249,521 -55%
ACM
61
Aquatic Capital Management
Illinois
$3.06M 176,704 -39,172 -18%
Invesco
62
Invesco
Georgia
$2.88M 166,135 -475,262 -74%
YIH
63
Y-Intercept (HK)
Hong Kong
$2.84M 164,275 +134,698 +455%
PP
64
PDT Partners
New York
$2.77M 160,058 -35,107 -18%
Bank of Montreal
65
Bank of Montreal
Ontario, Canada
$2.76M 159,613 +1,040 +0.7%
AG
66
Algert Global
California
$2.67M 154,113 -184,500 -54%
Prudential Financial
67
Prudential Financial
New Jersey
$2.67M 154,010 -63,870 -29%
VOYA Investment Management
68
VOYA Investment Management
Georgia
$2.61M 150,593 +25,192 +20%
Rafferty Asset Management
69
Rafferty Asset Management
New York
$2.49M 143,852 -36,282 -20%
Swiss National Bank
70
Swiss National Bank
Switzerland
$2.49M 143,800 +11,200 +8%
SPIA
71
Steward Partners Investment Advisory
New York
$2.44M 140,975 +18,800 +15%
Citigroup
72
Citigroup
New York
$2.4M 138,451 -278,168 -67%
California Public Employees Retirement System
73
California Public Employees Retirement System
California
$2.33M 134,637 +7,931 +6%
Carson Wealth (CWM LLC)
74
Carson Wealth (CWM LLC)
Nebraska
$2.21M 127,584 +29,326 +30%
RhumbLine Advisers
75
RhumbLine Advisers
Massachusetts
$2.11M 122,002 -2,452 -2%
1 2
3
4 5