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Apellis Pharmaceuticals
APLS

Overview Fund Activity

243 hedge funds and large institutions have $2.26B invested in Apellis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 43 funds opening new positions, 106 increasing their positions, 68 reducing their positions, and 49 closing their positions.

Holders
243
Holders Change
-11
Holders Change %
-4.33%
% of All Funds
3.26%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
43
Increased
106
Reduced
68
Closed
49
Calls
$47.3M
Puts
$9.73M
Net Calls
+$37.5M
Net Calls Change
+$30.8M

Top Buyers

1
Marshall Wace
1
Marshall Wace
United Kingdom
$46.8M
2
Norges Bank
2
Norges Bank
Norway
$41M
3
DTC
3
Deep Track Capital
Connecticut
$121M
4
AQR Capital Management
4
AQR Capital Management
Connecticut
$103M
5
UBS Group
5
UBS Group
Switzerland
$82M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$155M
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$334K
3
Man Group
3
Man Group
United Kingdom
$0
4
OCA
4
Octagon Capital Advisors
New York
$15.6M
5
National Bank of Canada
5
National Bank of Canada
Quebec, Canada
$0
Name Market Value Shares Shares
Change 		Shares
Change %
OCA
26
Octagon Capital Advisors
New York
$15.6M 903,500 -1,190,500 -57%
CCM
27
Camber Capital Management
Massachusetts
$14.7M 850,000 +850,000 New
Royal Bank of Canada
28
Royal Bank of Canada
Ontario, Canada
$13.8M 797,585 +2,650 +0.3%
Ameriprise
29
Ameriprise
Minnesota
$13M 750,161 +283,500 +61%
Bank of Nova Scotia
30
Bank of Nova Scotia
Ontario, Canada
$10.3M 594,812 +594,812 New
JFG
31
Jefferies Financial Group
New York
$10M 578,205 -21,050 -4%
JF
32
Jump Financial
Illinois
$9.67M 558,668 +293,075 +110%
O
33
Ossiam
France
$9.62M 555,953 +555,953 New
CLGM
34
Capitolis Liquid Global Markets
New York
$9.43M 544,600 +544,600 New
WP
35
Woodline Partners
California
$9.19M 530,923 +312,073 +143%
Northern Trust
36
Northern Trust
Illinois
$9.1M 525,882 +7,188 +1%
Hudson Bay Capital Management
37
Hudson Bay Capital Management
Connecticut
$8.22M 475,000 +164,300 +53%
NL
38
Nuveen LLC
North Carolina
$8.12M 469,253 -22,985 -5%
Voloridge Investment Management
39
Voloridge Investment Management
Florida
$8.11M 468,710 +214,920 +85%
Citadel Advisors
40
Citadel Advisors
Florida
$7.66M 442,560 +218,464 +97%
6CM
41
683 Capital Management
New York
$7.1M 410,000 +77,000 +23%
Two Sigma Investments
42
Two Sigma Investments
New York
$7.04M 406,913 +144,009 +55%
Pictet Asset Management
43
Pictet Asset Management
Switzerland
$6.07M 348,349 +33,507 +11%
IC
44
IEQ Capital
California
$6.01M 346,923 +55,065 +19%
Canada Pension Plan Investment Board
45
Canada Pension Plan Investment Board
Ontario, Canada
$5.83M 336,800 -711,900 -68%
Squarepoint
46
Squarepoint
New York
$5.7M 329,392 -113,401 -26%
TI
47
Trexquant Investment
Connecticut
$5.67M 327,421 -57,501 -15%
IG
48
ING Group
Netherlands
$5.34M 308,300 +124,100 +67%
UBS AM
49
UBS AM
Illinois
$5.23M 301,939 +79,305 +36%
Barclays
50
Barclays
United Kingdom
$4.74M 273,912 +82,675 +43%
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