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Apellis Pharmaceuticals
APLS

Overview Fund Activity

254 hedge funds and large institutions have $2.77B invested in Apellis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 90 increasing their positions, 75 reducing their positions, and 52 closing their positions.

Holders
254
Holders Change
-4
Holders Change %
-1.55%
% of All Funds
3.45%
Holding in Top 10
6
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.08%
New
51
Increased
90
Reduced
75
Closed
52
Calls
$26.6M
Puts
$19.8M
Net Calls
+$6.76M
Net Calls Change
-$64.2M

Top Buyers

1
AQR Capital Management
1
AQR Capital Management
Connecticut
$89.2M
2
Bank of America
2
Bank of America
North Carolina
$68.5M
3
O
3
OrbiMed
New York
$31.3M
4
Canada Pension Plan Investment Board
4
Canada Pension Plan Investment Board
Ontario, Canada
$22.9M
5
Man Group
5
Man Group
United Kingdom
$22.5M

Top Sellers

1
CWM
1
CIBC World Markets
New York
$0
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$0
3
Norges Bank
3
Norges Bank
Norway
$0
4
OCA
4
Octagon Capital Advisors
New York
$45.8M
5
Toronto Dominion Bank
5
Toronto Dominion Bank
Ontario, Canada
$3.55M
Name Market Value Shares Shares
Change 		Shares
Change %
Wellington Management Group
1
Wellington Management Group
Massachusetts
$269M 12,303,252 +502,403 +4%
ACA
2
Avoro Capital Advisors
New York
$267M 12,222,222 – –
EC
3
EcoR1 Capital
California
$260M 11,895,808 +4,965 +0%
Vanguard Group
4
Vanguard Group
Pennsylvania
$222M 10,130,356 +84,331 +0.8%
Morgan Stanley
5
Morgan Stanley
New York
$211M 9,626,123 -1,104 -0%
BlackRock
6
BlackRock
New York
$138M 6,329,598 -148,391 -2%
DTC
7
Deep Track Capital
Connecticut
$109M 5,000,000 +725,079 +17%
AQR Capital Management
8
AQR Capital Management
Connecticut
$89.2M 4,077,419 +2,220,977 +120%
State Street
9
State Street
Massachusetts
$86.2M 3,941,405 -583,750 -13%
UBS Group
10
UBS Group
Switzerland
$71.6M 3,272,194 +685,455 +26%
Bank of America
11
Bank of America
North Carolina
$68.5M 3,131,436 +1,451,223 +86%
SL
12
Siren LLC
Connecticut
$56.4M 2,578,396 -237,862 -8%
Jennison Associates
13
Jennison Associates
New York
$54.2M 2,477,531 -282,873 -10%
OCA
14
Octagon Capital Advisors
New York
$45.8M 2,094,000 -912,980 -30%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$42.7M 1,950,046 +111,094 +6%
Deutsche Bank
16
Deutsche Bank
Germany
$38.9M 1,776,576 -1,801 -0.1%
B
17
Braidwell
Connecticut
$36.1M 1,652,334 -446,532 -21%
SCM
18
Suvretta Capital Management
New York
$36M 1,646,615 +853,428 +108%
PCH
19
Polar Capital Holdings
United Kingdom
$34.5M 1,577,175 – –
Fidelity Investments
20
Fidelity Investments
Massachusetts
$32.9M 1,503,209 -624,456 -29%
O
21
OrbiMed
New York
$31.3M 1,432,300 +1,432,300 New
BNP Paribas Financial Markets
22
BNP Paribas Financial Markets
France
$24.3M 1,110,709 +259,886 +31%
Canada Pension Plan Investment Board
23
Canada Pension Plan Investment Board
Ontario, Canada
$22.9M 1,048,700 +1,013,500 +2,879%
Man Group
24
Man Group
United Kingdom
$22.5M 1,027,792 +978,500 +1,985%
Charles Schwab
25
Charles Schwab
California
$21.1M 964,499 -32,249 -3%
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