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APLS

Apellis Pharmaceuticals

Delisted

APLS was delisted on the 13th of May, 2026.

168 hedge funds and large institutions have $3.65B invested in Apellis Pharmaceuticals in 2020 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 51 increasing their positions, 60 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

164% more first-time investments, than exits

New positions opened: 37 | Existing positions closed: 14

135% more call options, than puts

Call options by funds: $16.3M | Put options by funds: $6.96M

100% more funds holding in top 10

Funds holding in top 10: 36 (+3)

98% more capital invested

Capital invested by funds: $1.85B → $3.65B (+$1.81B)

16% more funds holding

Funds holding: 145168 (+23)

2.16% more ownership

Funds ownership: 82.2%84.36% (+2.2%)

15% less repeat investments, than reductions

Existing positions increased: 51 | Existing positions reduced: 60

Holders
168
Holders Change
+23
Holders Change %
+15.86%
% of All Funds
2.97%
Holding in Top 10
6
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+100%
% of All Funds
0.11%
New
37
Increased
51
Reduced
60
Closed
14
Calls
$16.3M
Puts
$6.96M
Net Calls
+$9.36M
Net Calls Change
+$8.31M
Name Holding Trade Value Shares
Change
Change in
Stake
OCA
26
Octagon Capital Advisors
New York
$31.4M +$23.2M +548,374 New
VP
27
venBio Partners
California
$28.1M -$470K -11,113 -2%
D.E. Shaw & Co
28
D.E. Shaw & Co
New York
$23.7M +$1.19M +28,196 +7%
DCM
29
Driehaus Capital Management
Illinois
$22.3M +$81K +1,914 +0.5%
Charles Schwab
30
Charles Schwab
California
$21.5M +$257K +6,071 +2%
GTC
31
Ghost Tree Capital
New York
$18.6M +$13.7M +325,000 New
Fidelity International
32
Fidelity International
Bermuda
$18.3M +$8.03M +189,835 +147%
LGM
33
Logos Global Management
California
$17.2M +$12.7M +300,000 New
RPAM
34
Rhenman & Partners Asset Management
Sweden
$15.4M +$1.9M +45,000 +20%
Nuveen
35
Nuveen
North Carolina
$15.4M -$175K -4,131 -2%
Bank of New York Mellon
36
Bank of New York Mellon
New York
$14.5M +$670K +15,847 +7%
Millennium Management
37
Millennium Management
New York
$13.8M -$28.6M -674,989 -74%
CCP
38
Clough Capital Partners
Massachusetts
$13.3M -$7.33M -173,385 -43%
ABG
39
Ally Bridge Group
New York
$13.2M +$9.73M +230,000 New
Man Group
40
Man Group
United Kingdom
$12.7M -$1.13M -26,686 -11%
Renaissance Technologies
41
Renaissance Technologies
New York
$12.4M +$9.15M +216,313 New
TCM
42
Tekla Capital Management
Massachusetts
$12.4M
Axa
43
Axa
France
$12.1M +$917K +21,681 +11%
Two Sigma Investments
44
Two Sigma Investments
New York
$11.7M -$4.49M -106,240 -34%
ACP
45
Acuta Capital Partners
California
$9.55M
Prudential Financial
46
Prudential Financial
New Jersey
$9.43M +$1.71M +40,490 +33%
Bank of Montreal
47
Bank of Montreal
Ontario, Canada
$8.97M -$7.78M -183,981 -54%
Bank of America
48
Bank of America
North Carolina
$8.67M +$1.17M +27,681 +22%
California Public Employees Retirement System
49
California Public Employees Retirement System
California
$8.01M +$154K +3,644 +3%
AA
50
ALPS Advisors
Colorado
$7.82M +$1.7M +40,239 +42%

APLS Hedge Fund Activity: Q4 2020 in Review

168 of the 5,652 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q4 2020, worth a combined $3.65B — up 98% from $1.85B a quarter earlier.

Buyers outnumbered sellers: 37 funds opened new APLS positions and 14 closed out — a net gain of 23 holders — while 51 added to existing stakes and 60 trimmed.

The largest buyer was Vanguard Group, adding an estimated $51.8M. The largest seller was Citadel Advisors, cutting an estimated $32.4M.

  • 168 institutional investors held Apellis Pharmaceuticals (APLS) as of Q4 2020, up from 145 in Q3 2020.
  • Funds reported $3.65B of Apellis Pharmaceuticals stock for Q4 2020, up 98% quarter-over-quarter.
  • 37 funds opened new Apellis Pharmaceuticals positions in Q4 2020 and 14 closed out, a net change of +23 holders.
  • The largest Apellis Pharmaceuticals buyer in Q4 2020 was Vanguard Group, an estimated $51.8M added.
  • The largest Apellis Pharmaceuticals seller in Q4 2020 was Citadel Advisors, an estimated $32.4M sold.

Based on aggregated 13F filings for Q4 2020.