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Annexon

165 hedge funds and large institutions have $687M invested in Annexon in 2025 Q4 according to their latest regulatory filings, with 40 funds opening new positions, 71 increasing their positions, 29 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
165
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$4.31M
Puts
$2.71M
Net Calls
Net Calls Change

Top Buyers

1 +$15.3M
2 +$14.3M
3 +$11.9M
4
MCO
MAK Capital One
New York
+$11.3M
5
State Street
State Street
Massachusetts
+$9.95M

Top Sellers

1 -$7.73M
2 -$3.61M
3 -$3.28M
4
RPAM
Rhenman & Partners Asset Management
Sweden
-$2.51M
5
Goldman Sachs
Goldman Sachs
New York
-$2.44M
Name Holding Trade Value Shares
Change
Change in
Stake
VPIM
126
Vanguard Personalized Indexing Management
California
$64.8K
PCM
127
Prelude Capital Management
New York
$60.2K
Cambridge Investment Research Advisors
128
Cambridge Investment Research Advisors
Iowa
$54K
MVA
129
Mount Vernon Associates
Maryland
$53K
Mercer Global Advisors
130
Mercer Global Advisors
Colorado
$52.1K
Simplex Trading
131
Simplex Trading
Illinois
$51.5K
LCM
132
Landscape Capital Management
New Jersey
$50.3K
HA
133
Harbor Advisors
Florida
$50.2K
AIP
134
Ameritas Investment Partners
Nebraska
$48.6K
Legal & General Group
135
Legal & General Group
United Kingdom
$46.7K
Mirae Asset Global Investments
136
Mirae Asset Global Investments
South Korea
$35.3K
California State Teachers Retirement System (CalSTRS)
137
California State Teachers Retirement System (CalSTRS)
California
$30.9K
GWM
138
Geneos Wealth Management
Colorado
$30.1K
SCM
139
Sterling Capital Management
North Carolina
$30K
AB
140
Amalgamated Bank
New York
$16K
Royal Bank of Canada
141
Royal Bank of Canada
Ontario, Canada
$15K
Jones Financial Companies
142
Jones Financial Companies
Missouri
$15K
GFM
143
GF Fund Management
China
$14.3K
Nisa Investment Advisors
144
Nisa Investment Advisors
Missouri
$13.1K
LFG
145
Larson Financial Group
Missouri
$10K
TRCT
146
Tower Research Capital (TRC)
New York
$9.87K
PNC Financial Services Group
147
PNC Financial Services Group
Pennsylvania
$5.68K
Federated Hermes
148
Federated Hermes
Pennsylvania
$3.78K
IA
149
IFP Advisors
Florida
$2.75K
EWA
150
EverSource Wealth Advisors
Alabama
$2.71K