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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Investments
301
Two Sigma Investments
New York
$21.6M +$21.2M +73,182 +2,257%
BF
302
BOK Financial
Oklahoma
$21.4M -$282K -972 -1%
SMFG
303
Sumitomo Mitsui Financial Group
Japan
$21.4M +$1.58M +5,457 +8%
PAM
304
Palisade Asset Management
Minnesota
$21.1M +$218K +750 +1%
Allspring Global Investments
305
Allspring Global Investments
North Carolina
$20.8M +$1.25M +4,323 +7%
SCTC
306
Sanibel Captiva Trust Company
Florida
$20.7M -$345K -1,188 -2%
AIM
307
Avity Investment Management
Connecticut
$20.7M -$9.5M -32,766 -31%
GGI
308
Godsey & Gibb Inc
Virginia
$20.7M +$180K +619 +0.9%
NYLIM
309
New York Life Investment Management
New York
$20.6M -$146K -505 -0.7%
QCM
310
QRG Capital Management
Illinois
$20.6M -$7.79M -26,849 -27%
RBI
311
Raiffeisen Bank International
Austria
$20.6M +$1.42M +4,886 +7%
JGC
312
J. Goldman & Co
New York
$20.5M +$21.1M +72,802 New
Calamos Advisors
313
Calamos Advisors
Illinois
$20.5M +$70.8K +244 +0.3%
TIP
314
Torray Investment Partners
Maryland
$20.5M +$775K +2,672 +4%
GIP
315
Greatmark Investment Partners
Georgia
$20.4M +$16.8K +58 +0.1%
VPIM
316
Vanguard Personalized Indexing Management
California
$20.3M -$142K -489 -0.7%
SGK
317
Steigerwald Gordon & Koch
Virginia
$20.1M +$139K +479 +0.7%
BCM
318
Brookstone Capital Management
Illinois
$20.1M +$4.65M +16,042 +29%
ClearBridge Investments
319
ClearBridge Investments
New York
$20.1M +$128K +443 +0.6%
ACM
320
Advisors Capital Management
New Jersey
$20M +$608K +2,095 +3%
FLII
321
First Long Island Investors
New York
$19.9M -$117K -404 -0.6%
Wealthfront Advisers
322
Wealthfront Advisers
California
$19.8M +$3.73M +12,857 +22%
TS
323
Tamar Securities
California
$19.8M +$728K +2,509 +4%
MPM
324
MBB Public Markets
Illinois
$19.7M
WB
325
WesBanco Bank
West Virginia
$19.7M +$778K +2,684 +4%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.