Amgen
AMGN
2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.
8% more first-time investments, than exits
New positions opened: 144 | Existing positions closed: 133
8% more call options, than puts
Call options by funds: $1.88B | Put options by funds: $1.74B
1% less capital invested
Capital invested by funds: $121B → $119B (-$1.21B)
3% less repeat investments, than reductions
Existing positions increased: 1,122 | Existing positions reduced: 1,153
1% less funds holding
Funds holding: 2,851 → 2,819 (-32)
1.78% less ownership
Funds ownership: 80.37% → 78.59% (-1.8%)
28% less funds holding in top 10
Funds holding in top 10: 40 → 29 (-11)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Capital World Investors
Los Angeles,
California
|
+$561M |
| 2 |
National Bank of Canada
Montreal,
Quebec, Canada
|
+$251M |
| 3 |
Charles Schwab
San Francisco,
California
|
+$191M |
| 4 |
VanEck Associates
New York
|
+$165M |
| 5 |
Fisher Asset Management
Camas,
Washington
|
+$109M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Primecap Management
Pasadena,
California
|
-$268M |
| 2 |
UBS AM
Chicago,
Illinois
|
-$213M |
| 3 |
WF
WoodTrust Financial
Wisconsin Rapids,
Wisconsin
|
-$171M |
| 4 |
BlackRock
New York
|
-$164M |
| 5 |
D.E. Shaw & Co
New York
|
-$144M |
AMGN Hedge Fund Activity: Q3 2025 in Review
2,819 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.
Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.
The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.
- 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
- Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
- 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
- The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
- The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.
Based on aggregated 13F filings for Q3 2025.