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2,826 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,130 increasing their positions, 1,153 reducing their positions, and 132 closing their positions.

New
Increased
Maintained
Reduced
Closed

9% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 132

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.18B)

2% less repeat investments, than reductions

Existing positions increased: 1,130 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8562,826 (-30)

1.69% less ownership

Funds ownership: 80.28%78.59% (-1.7%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,826
Holders Change
-30
Holders Change %
-1.05%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,130
Reduced
1,153
Closed
132
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M

AMGN Hedge Fund Activity: Q3 2025 in Review

2,826 of the 7,640 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 0.98% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 132 closed out — a net gain of 12 holders — while 1,130 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,826 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,856 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 0.98% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 132 closed out, a net change of +12 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.