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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$15B +$238M +841,117 +2%
BlackRock
2
BlackRock
New York
$13B +$328M +1,158,907 +3%
State Street
3
State Street
Massachusetts
$8.2B +$50.2M +177,035 +0.6%
Capital International Investors
4
Capital International Investors
California
$5.28B +$1.07B +3,775,911 +25%
Capital World Investors
5
Capital World Investors
California
$4.71B +$44.8M +157,989 +0.9%
Morgan Stanley
6
Morgan Stanley
New York
$4.52B -$14M -49,340 -0.3%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$3.62B +$82.5M +291,271 +2%
Charles Schwab
8
Charles Schwab
California
$3.6B +$195M +687,735 +6%
Primecap Management
9
Primecap Management
California
$2.97B -$498M -1,756,586 -14%
Wells Fargo
10
Wells Fargo
California
$2.04B +$16.8M +59,477 +0.8%
Northern Trust
11
Northern Trust
Illinois
$1.71B -$18.2M -64,298 -1%
Norges Bank
12
Norges Bank
Norway
$1.66B +$86.8M +306,306 +5%
Bank of America
13
Bank of America
North Carolina
$1.56B +$120M +422,361 +8%
UBS AM
14
UBS AM
Illinois
$1.47B +$179M +630,097 +14%
Capital Research Global Investors
15
Capital Research Global Investors
California
$1.29B +$25.6M +90,189 +2%
UBS Group
16
UBS Group
Switzerland
$1.28B +$25.9M +91,273 +2%
Royal Bank of Canada
17
Royal Bank of Canada
Ontario, Canada
$1.27B -$98.2M -346,595 -7%
Goldman Sachs
18
Goldman Sachs
New York
$1.18B -$49.6M -174,963 -4%
Invesco
19
Invesco
Georgia
$1.17B +$96.3M +339,755 +9%
Bank of New York Mellon
20
Bank of New York Mellon
New York
$1.12B -$127M -446,593 -10%
JP Morgan Chase
21
JP Morgan Chase
New York
$1.08B +$12.9M +45,523 +1%
Fidelity Investments
22
Fidelity Investments
Massachusetts
$1.02B -$59.6M -210,387 -5%
Aristotle Capital Management
23
Aristotle Capital Management
California
$1.01B -$21.3M -75,345 -2%
Legal & General Group
24
Legal & General Group
United Kingdom
$988M -$34.5M -121,632 -3%
Dimensional Fund Advisors
25
Dimensional Fund Advisors
Texas
$844M +$958K +3,381 +0.1%

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.