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2,861 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 143 funds opening new positions, 1,238 increasing their positions, 1,099 reducing their positions, and 181 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more capital inflows, than outflows

Capital inflows: $5.65B | Capital outflows: $4.73B

13% more repeat investments, than reductions

Existing positions increased: 1,238 | Existing positions reduced: 1,099

0.45% more ownership

Funds ownership: 79.83% → 80.28% (+0.45%)

3% less funds holding

Funds holding: 2,938 → 2,861 (-77)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

21% less first-time investments, than exits

New positions opened: 143 | Existing positions closed: 181

46% less funds holding in top 10

Funds holding in top 10: 74 → 40 (-34)

Holders
2,861
Holders Change
-77
Holders Change %
-2.62%
% of All Funds
37.51%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.52%
New
143
Increased
1,238
Reduced
1,099
Closed
181
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M

AMGN Hedge Fund Activity: Q2 2025 in Review

2,861 of the 7,628 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $134B a quarter earlier.

Sellers outnumbered buyers: 181 funds closed out of AMGN and 143 opened new positions — a net loss of 38 holders — while 1,099 trimmed existing stakes and 1,238 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,861 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,938 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 143 funds opened new Amgen positions in Q2 2025 and 181 closed out, a net change of -38 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.