Two Sigma Investments’s Amgen AMGN Stock Holding History

Two Sigma Investments’s Portfolio AMGN Stock Details AMGN Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$25.2M	Sell	71,680 -628,708	-90%	-$224M	0.02%	813
2025 Q4	$229M	Buy	700,388 +623,963	+816%	+$198M	0.32%	43
2025 Q3	$21.6M	Buy	76,425 +73,182	+2,257%	+$21.2M	0.03%	608
2025 Q2	$905K	Sell	3,243 -356,273	-99%	-$101M	﹤0.01%	2302
2025 Q1	$112M	Sell	359,516 -542,770	-60%	-$160M	0.24%	99
2024 Q4	$235M	Buy	902,286 +543,545	+152%	+$161M	0.51%	28
2024 Q3	$116M	Sell	358,741 -183,407	-34%	-$60M	0.25%	96
2024 Q2	$169M	Buy	542,148 +429,765	+382%	+$126M	0.39%	57
2024 Q1	$32M	Buy	112,383 +15,142	+16%	+$4.43M	0.08%	312
2023 Q4	$28M	Sell	97,241 -618,747	-86%	-$169M	0.06%	337
2023 Q3	$192M	Sell	715,988 -270,913	-27%	-$67.6M	0.52%	30
2023 Q2	$219M	Buy	986,901 +41,426	+4%	+$9.61M	0.55%	19
2023 Q1	$229M	Buy	945,475 +17,524	+2%	+$4.3M	0.65%	16
2022 Q4	$244M	Sell	927,951 -2,284	-0.2%	-$612K	0.77%	7
2022 Q3	$210M	Buy	930,235 +126,402	+16%	+$30.6M	0.71%	18
2022 Q2	$196M	Sell	803,833 -241,382	-23%	-$59.2M	0.65%	28
2022 Q1	$253M	Buy	1,045,215 +52,923	+5%	+$12.2M	0.75%	3
2021 Q4	$223M	Sell	992,292 -72,653	-7%	-$15.3M	0.48%	24
2021 Q3	$226M	Buy	1,064,945 +125,064	+13%	+$28.8M	0.51%	12
2021 Q2	$229M	Buy	+939,881	New	+$231M	0.52%	21
2021 Q1	–	Sell	-6,100	Closed	-$1.46M	–	3777
2020 Q4	$1.4M	Buy	+6,100	New	+$1.41M	﹤0.01%	1750
2020 Q3	–	Sell	-325,550	Closed	-$80.7M	–	3049
2020 Q2	$76.8M	Buy	325,550 +182,669	+128%	+$41.7M	0.38%	51
2020 Q1	$29M	Buy	142,881 +114,548	+404%	+$25M	0.24%	76
2019 Q4	$6.83M	Sell	28,333 -65,483	-70%	-$14.4M	0.02%	778
2019 Q3	$18.2M	Sell	93,816 -593,662	-86%	-$114M	0.06%	374
2019 Q2	$127M	Buy	687,478 +30,676	+5%	+$5.49M	0.42%	34
2019 Q1	$125M	Buy	656,802 +570,716	+663%	+$109M	0.4%	33
2018 Q4	$16.8M	Sell	86,086 -194,584	-69%	-$38M	0.07%	373
2018 Q3	$58.2M	Sell	280,670 -307,799	-52%	-$60.7M	0.16%	192
2018 Q2	$109M	Buy	588,469 +383,825	+188%	+$67.9M	0.32%	55
2018 Q1	$34.9M	Sell	204,644 -366,739	-64%	-$67.3M	0.12%	218
2017 Q4	$99.4M	Buy	571,383 +79,938	+16%	+$14.1M	0.32%	52
2017 Q3	$91.6M	Sell	491,445 -109,286	-18%	-$19.4M	0.32%	70
2017 Q2	$103M	Buy	600,731 +228,078	+61%	+$37.1M	0.37%	51
2017 Q1	$61.1M	Sell	372,653 -125,351	-25%	-$20.8M	0.21%	114
2016 Q4	$72.8M	Buy	498,004 +443,531	+814%	+$66.8M	0.28%	72
2016 Q3	$9.09M	Sell	54,473 -564,872	-91%	-$95.5M	0.03%	585
2016 Q2	$94.2M	Sell	619,345 -28,213	-4%	-$4.39M	0.4%	49
2016 Q1	$97.1M	Buy	647,558 +446,275	+222%	+$66.3M	0.46%	42
2015 Q4	$32.7M	Sell	201,283 -611,999	-75%	-$96.2M	0.16%	158
2015 Q3	$112M	Sell	813,282 -241,626	-23%	-$38.1M	0.58%	34
2015 Q2	$162M	Buy	1,054,908 +508,757	+93%	+$81.5M	0.76%	4
2015 Q1	$87.3M	Buy	+546,151	New	+$86M	0.41%	39
2014 Q4	–	Sell	-149,268	Closed	-$21M	–	2203
2014 Q3	$21M	Sell	149,268 -959,264	-87%	-$125M	0.09%	281
2014 Q2	$131M	Buy	+1,108,532	New	+$128M	0.59%	17
2014 Q1	–	Sell	-317,965	Closed	-$36.3M	–	1960
2013 Q4	$36.3M	Buy	+317,965	New	+$36.2M	0.2%	128

Other funds holding AMGN

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return

Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Charles Schwab San Francisco, California $654B AUM 26.35% 1-Year Est. Return

Primecap Management Pasadena, California $127B AUM 44.11% 1-Year Est. Return

Two Sigma Investments's AMGN Position: Q1 2026 in Review

Two Sigma Investments reduced its Amgen (AMGN) stake by 90% in Q1 2026, selling an estimated $224M and leaving 71,680 shares worth $25.2M. The position accounts for 0.02% of the portfolio, ranked #813.

Two Sigma Investments first reported a position in AMGN in Q4 2013 and has held it in 46 quarters since. The position peaked at $253M in Q1 2022. 3,127 funds tracked by Wall St. Rank hold AMGN as of Q1 2026.

Two Sigma Investments held 71,680 shares of Amgen worth $25.2M as of Q1 2026.
Two Sigma Investments sold 628,708 Amgen shares in Q1 2026, an estimated $224M.
Amgen made up 0.02% of Two Sigma Investments's portfolio in Q1 2026, its #813 holding.
Two Sigma Investments first reported a position in Amgen in Q4 2013 and has held it in 46 quarters since.
Two Sigma Investments's Amgen position peaked at $253M in Q1 2022.
3,127 funds tracked by Wall St. Rank held Amgen as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.