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Alnylam Pharmaceuticals

Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$2.62B -$289M -1,894,704 -11%
Vanguard Group
2
Vanguard Group
Pennsylvania
$1.77B +$19.3M +126,373 +1%
Baillie Gifford & Co
3
Baillie Gifford & Co
United Kingdom
$1.66B -$72.7M -477,022 -4%
BlackRock
4
BlackRock
New York
$1.24B -$9.51M -62,448 -0.8%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$1.15B +$29M +190,057 +3%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$1.11B +$39.4M +258,798 +4%
Capital World Investors
7
Capital World Investors
California
$980M +$865M +5,680,728 +1,781%
Dodge & Cox
8
Dodge & Cox
California
$894M +$6.79M +44,600 +0.8%
JP Morgan Chase
9
JP Morgan Chase
New York
$477M -$8.09M -53,070 -2%
State Street
10
State Street
Massachusetts
$475M +$9M +59,101 +2%
Manulife (Manufacturers Life Insurance)
11
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$286M +$7.37M +48,393 +3%
RI
12
RTW Investments
New York
$275M -$44.6M -292,517 -15%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$256M +$9.9M +64,992 +4%
ACA
14
Avoro Capital Advisors
New York
$212M +$34.3M +225,000 +21%
Norges Bank
15
Norges Bank
Norway
$211M +$3.95M +25,896 +2%
BG
16
Bellevue Group
Switzerland
$201M -$16.1M -105,577 -8%
American Century Companies
17
American Century Companies
Missouri
$185M +$19.7M +129,270 +13%
FCM
18
Farallon Capital Management
California
$167M -$25.3M -166,155 -14%
CC
19
Casdin Capital
New York
$163M
Invesco
20
Invesco
Georgia
$158M +$12M +78,665 +9%
Amundi
21
Amundi
France
$142M +$94.6M +620,695 +244%
Loomis, Sayles & Company
22
Loomis, Sayles & Company
Massachusetts
$142M -$19.5M -127,689 -13%
Morgan Stanley
23
Morgan Stanley
New York
$139M -$33.1M -217,032 -20%
Holocene Advisors
24
Holocene Advisors
New York
$131M +$11.7M +76,483 +11%
GGHC
25
Gilder Gagnon Howe & Co
New York
$129M -$7.37M -48,344 -6%