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Alnylam Pharmaceuticals
ALNY

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$289M +$248M +9,325,655 New
Vanguard Group
2
Vanguard Group
Pennsylvania
$84.8M +$72.7M +2,733,748 New
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$71.6M +$61.4M +2,308,100 New
BFA
4
BlackRock Fund Advisors
California
$59.3M +$50.9M +1,911,485 New
Capital World Investors
5
Capital World Investors
California
$52.7M +$45.2M +1,700,000 New
GGHC
6
Gilder Gagnon Howe & Co
New York
$52M +$44.6M +1,676,428 New
State Street
7
State Street
Massachusetts
$49.3M +$42.3M +1,588,309 New
BIT
8
BlackRock Institutional Trust
California
$45.7M +$39.2M +1,473,318 New
UBS AM
9
UBS AM
Illinois
$41.7M +$35.8M +1,345,879 New
Citadel Advisors
10
Citadel Advisors
Florida
$36.8M +$31.6M +1,187,896 New
BA
11
BlackRock Advisors
Delaware
$36.3M +$31.1M +1,169,951 New
CWAM
12
Columbia Wanger Asset Management
Illinois
$34M +$29.2M +1,098,000 New
Wells Fargo
13
Wells Fargo
California
$33.3M +$28.6M +1,074,529 New
SPC
14
Slate Path Capital
New York
$32.5M +$27.9M +1,050,000 New
Lord, Abbett & Co
15
Lord, Abbett & Co
New Jersey
$31.8M +$27.3M +1,026,502 New
BM
16
Bridger Management
New York
$31.8M +$27.3M +1,026,648 New
CCM
17
Camber Capital Management
Massachusetts
$31M +$26.6M +1,000,000 New
Jennison Associates
18
Jennison Associates
New York
$30.6M +$26.2M +985,933 New
Baillie Gifford & Co
19
Baillie Gifford & Co
United Kingdom
$27.9M +$24M +900,900 New
Northern Trust
20
Northern Trust
Illinois
$24.5M +$21M +789,455 New
DM
21
Deerfield Management
New York
$21.5M +$18.5M +694,000 New
Ameriprise
22
Ameriprise
Minnesota
$20.5M +$17.6M +662,625 New
SCA
23
SAC Capital Advisors
Connecticut
$19.2M +$16.5M +620,449 New
CCI
24
Columbus Circle Investors
$19.1M +$16.4M +615,922 New
Bank of New York Mellon
25
Bank of New York Mellon
New York
$17.6M +$15.1M +567,590 New
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