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Alnylam Pharmaceuticals

Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$3.37B +$36.6M +195,199 +1%
Vanguard Group
2
Vanguard Group
Pennsylvania
$2B +$21.9M +116,888 +1%
Baillie Gifford & Co
3
Baillie Gifford & Co
United Kingdom
$1.97B +$35.8M +190,925 +2%
BlackRock
4
BlackRock
New York
$1.68B +$42.1M +224,569 +3%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$1.39B -$339M -1,807,417 -20%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$1.11B +$65.6M +349,557 +6%
Dodge & Cox
7
Dodge & Cox
California
$1.01B -$7.86M -41,901 -0.8%
State Street
8
State Street
Massachusetts
$529M +$2.98M +15,887 +0.6%
JP Morgan Chase
9
JP Morgan Chase
New York
$462M -$26.8M -142,851 -6%
Morgan Stanley
10
Morgan Stanley
New York
$355M -$332K -1,772 -0.1%
Manulife (Manufacturers Life Insurance)
11
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$327M -$4.57M -24,375 -1%
RI
12
RTW Investments
New York
$318M
Geode Capital Management
13
Geode Capital Management
Massachusetts
$274M +$1.5M +8,001 +0.6%
BG
14
Bellevue Group
Switzerland
$266M -$26.4M -140,674 -9%
Massachusetts Financial Services
15
Massachusetts Financial Services
Massachusetts
$258M -$1.85M -9,856 -0.7%
American Century Companies
16
American Century Companies
Missouri
$202M +$4.74M +25,281 +2%
Invesco
17
Invesco
Georgia
$199M +$9.81M +52,271 +5%
CC
18
Casdin Capital
New York
$189M
Norges Bank
19
Norges Bank
Norway
$188M +$18.8M +100,136 +11%
Loomis, Sayles & Company
20
Loomis, Sayles & Company
Massachusetts
$183M +$4.13M +22,042 +2%
Federated Hermes
21
Federated Hermes
Pennsylvania
$181M -$4.36M -23,258 -2%
GGHC
22
Gilder Gagnon Howe & Co
New York
$174M -$383K -2,042 -0.2%
ACA
23
Avoro Capital Advisors
New York
$160M -$28.1M -150,000 -15%
PAMS
24
Pictet Asset Management (Switzerland)
Switzerland
$156M +$155M +823,704 New
FCM
25
Farallon Capital Management
California
$154M -$25.5M -135,699 -14%