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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
PCMH
176
Polymer Capital Management (HK)
Hong Kong
$14.6M
ASRS
177
Arizona State Retirement System
Arizona
$14.5M
GAM
178
Groupama Asset Management
France
$14.3M
NAM
179
Nissay Asset Management
Japan
$14.2M
Lord, Abbett & Co
180
Lord, Abbett & Co
New Jersey
$14.1M
PPF
181
PFA Pension Forsikringsaktieselskab
$14.1M
Bank of Montreal
182
Bank of Montreal
Ontario, Canada
$14M
EAM
183
Eventide Asset Management
Massachusetts
$13.5M
RSS
184
Rosenblum Silverman Sutton
California
$13.2M
TRSOTSOK
185
Teachers Retirement System of the State of Kentucky
Kentucky
$12.6M
PAM
186
Panagora Asset Management
Massachusetts
$12.3M
DnB Asset Management
187
DnB Asset Management
Norway
$12.2M
JF
188
Jump Financial
Illinois
$12.2M
GFM
189
GF Fund Management
China
$12.1M
ZIG
190
Zurich Insurance Group
Switzerland
$12.1M
FAF
191
Fjarde Ap-fonden
Sweden
$12M
OBAM
192
ODDO BHF Asset Management
France
$12M
CIBC Asset Management
193
CIBC Asset Management
Ontario, Canada
$11.9M
SO
194
STRS Ohio
Ohio
$11.1M
USCWA
195
U.S. Capital Wealth Advisors
Texas
$10.9M
X
196
Xponance
Pennsylvania
$10.9M
TI
197
Trexquant Investment
Connecticut
$10.6M
EI
198
EFG International
$10.5M
JFG
199
Jefferies Financial Group
New York
$10.5M
II
200
IFM Investors
Australia
$10.4M