ALNY icon

Alnylam Pharmaceuticals

832 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 283 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 283 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.57B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
832
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
Lord, Abbett & Co
176
Lord, Abbett & Co
New Jersey
$14.1M
PPF
177
PFA Pension Forsikringsaktieselskab
$14.1M
Bank of Montreal
178
Bank of Montreal
Ontario, Canada
$14M
EAM
179
Eventide Asset Management
Massachusetts
$13.5M
RSS
180
Rosenblum Silverman Sutton
California
$13.2M
TRSOTSOK
181
Teachers Retirement System of the State of Kentucky
Kentucky
$12.6M
PAM
182
Panagora Asset Management
Massachusetts
$12.3M
DnB Asset Management
183
DnB Asset Management
Norway
$12.2M
JF
184
Jump Financial
Illinois
$12.2M
GFM
185
GF Fund Management
China
$12.1M
ZIG
186
Zurich Insurance Group
Switzerland
$12.1M
FAF
187
Fjarde Ap-fonden
Sweden
$12M
OBAM
188
ODDO BHF Asset Management
France
$12M
CIBC Asset Management
189
CIBC Asset Management
Ontario, Canada
$11.9M
SO
190
STRS Ohio
Ohio
$11.1M
USCWA
191
U.S. Capital Wealth Advisors
Texas
$10.9M
X
192
Xponance
Pennsylvania
$10.9M
TI
193
Trexquant Investment
Connecticut
$10.6M
EI
194
EFG International
$10.5M
JFG
195
Jefferies Financial Group
New York
$10.5M
II
196
IFM Investors
Australia
$10.4M
UIM
197
USS Investment Management
United Kingdom
$10.4M
VMPIC
198
Varma Mutual Pension Insurance Co
Finland
$10.4M
EAM
199
Erste Asset Management
Austria
$10.4M
Daiwa Securities Group
200
Daiwa Securities Group
Japan
$10.3M