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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
IIM
151
INTECH Investment Management
Florida
$18.6M
FAF
152
Första AP-fonden
Sweden
$18.5M
LPL Financial
153
LPL Financial
California
$18.3M
DekaBank Deutsche Girozentrale
154
DekaBank Deutsche Girozentrale
Germany
$18.2M
RPAM
155
Rhenman & Partners Asset Management
Sweden
$18.2M
Rafferty Asset Management
156
Rafferty Asset Management
New York
$17.9M
State of New Jersey Common Pension Fund D
157
State of New Jersey Common Pension Fund D
New Jersey
$17.9M
SSA
158
Schonfeld Strategic Advisors
New York
$17.9M
Osaic Holdings
159
Osaic Holdings
Arizona
$17.8M
Parnassus Investments
160
Parnassus Investments
California
$17.7M
Ohio Public Employees Retirement System (OPERS)
161
Ohio Public Employees Retirement System (OPERS)
Ohio
$17.7M
Natixis Advisors
162
Natixis Advisors
Massachusetts
$17.6M
AllianceBernstein
163
AllianceBernstein
Tennessee
$17.6M
Mariner
164
Mariner
Kansas
$16.9M
MIF
165
Mediolanum International Funds
Ireland
$16.9M
LF
166
Lansforsakringar Fondforvaltning
Sweden
$16.8M
NIM
167
NEOS Investment Management
Connecticut
$16.2M
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
168
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$16.1M
TAF
169
Tredje AP-fonden
Sweden
$16.1M
GC
170
Guggenheim Capital
Illinois
$16M
N
171
Natixis
France
$15.8M
GAM
172
Gotham Asset Management
New York
$15.8M
RAM
173
Resona Asset Management
Japan
$15.6M
BCM
174
Bronte Capital Management
Australia
$15.5M
Citadel Advisors
175
Citadel Advisors
Florida
$15.3M