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Alnylam Pharmaceuticals

832 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 283 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 283 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.57B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
832
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
State of Wisconsin Investment Board
126
State of Wisconsin Investment Board
Wisconsin
$26.3M
Asset Management One
127
Asset Management One
Japan
$26M
IC
128
IEQ Capital
California
$25.8M
New York State Common Retirement Fund
129
New York State Common Retirement Fund
New York
$25.6M
Manulife (Manufacturers Life Insurance)
130
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$25.2M
Swedbank
131
Swedbank
Sweden
$24.6M
IHAM
132
Integral Health Asset Management
New York
$23.9M
CII
133
Capital International Inc
California
$23.7M
LP
134
LMR Partners
United Kingdom
$23.5M
Ensign Peak Advisors
135
Ensign Peak Advisors
Utah
$23M
Canada Life
136
Canada Life
Manitoba, Canada
$23M
Treasurer of the State of North Carolina
137
Treasurer of the State of North Carolina
North Carolina
$21.1M
Caisse de Depot et Placement du Quebec (CDPQ)
138
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$20.5M
VCM
139
Voleon Capital Management
California
$20.3M
KK
140
KLP Kapitalforvaltning
Norway
$20.1M
Mirae Asset Global Investments
141
Mirae Asset Global Investments
South Korea
$19.7M
FCM
142
Frontier Capital Management
Massachusetts
$19.4M
AAF
143
Andra AP-fonden
Sweden
$19.3M
VanEck Associates
144
VanEck Associates
New York
$19.1M
AP
145
Antipodes Partners
Australia
$19M
Allianz Asset Management
146
Allianz Asset Management
Germany
$19M
PHP
147
Parkman Healthcare Partners
Connecticut
$19M
IIM
148
INTECH Investment Management
Florida
$18.6M
FAF
149
Första AP-fonden
Sweden
$18.5M
LPL Financial
150
LPL Financial
California
$18.3M