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Alnylam Pharmaceuticals

832 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 283 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 283 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.57B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
832
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
California State Teachers Retirement System (CalSTRS)
76
California State Teachers Retirement System (CalSTRS)
California
$80.3M
CIBC Private Wealth Group
77
CIBC Private Wealth Group
Georgia
$79.7M
VOYA Investment Management
78
VOYA Investment Management
Georgia
$79M
RhumbLine Advisers
79
RhumbLine Advisers
Massachusetts
$77.6M
Susquehanna International Group
80
Susquehanna International Group
Pennsylvania
$76.3M
Korea Investment Corp
81
Korea Investment Corp
South Korea
$75.5M
Ameriprise
82
Ameriprise
Minnesota
$72M
Citigroup
83
Citigroup
New York
$68.6M
National Pension Service
84
National Pension Service
South Korea
$66.9M
Russell Investments Group
85
Russell Investments Group
United Kingdom
$65.9M
Voloridge Investment Management
86
Voloridge Investment Management
Florida
$63.9M
SCM
87
SCS Capital Management
Massachusetts
$59.5M
Robeco Institutional Asset Management
88
Robeco Institutional Asset Management
Netherlands
$57.5M
Man Group
89
Man Group
United Kingdom
$57.3M
Mitsubishi UFJ Asset Management
90
Mitsubishi UFJ Asset Management
Japan
$55.5M
Janus Henderson Group
91
Janus Henderson Group
United Kingdom
$54.3M
Handelsbanken Fonder
92
Handelsbanken Fonder
Sweden
$54.2M
Aberdeen Group
93
Aberdeen Group
United Kingdom
$52.8M
Universal-Beteiligungs- und Servicegesellschaft
94
Universal-Beteiligungs- und Servicegesellschaft
Germany
$49.4M
Envestnet Asset Management
95
Envestnet Asset Management
Illinois
$47.9M
CIS
96
Capital International Sarl
California
$47.5M
Neuberger Berman Group
97
Neuberger Berman Group
New York
$45.8M
State Board of Administration of Florida Retirement System
98
State Board of Administration of Florida Retirement System
Florida
$45.6M
SEI Investments
99
SEI Investments
Pennsylvania
$44.2M
Aviva
100
Aviva
United Kingdom
$44M