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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+29
Holders Change %
+4.7%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
62
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
National Pension Service
76
National Pension Service
South Korea
$57.1M +$452K +1,387 +0.8%
SCM
77
SCS Capital Management
Massachusetts
$55.7M -$135K -415 -0.2%
Arrowstreet Capital
78
Arrowstreet Capital
Massachusetts
$55.3M +$54M +165,645 +4,085%
Victory Capital Management
79
Victory Capital Management
Texas
$51M +$38.7M +118,645 +315%
Handelsbanken Fonder
80
Handelsbanken Fonder
Sweden
$50.7M +$12.6M +38,679 +33%
Janus Henderson Group
81
Janus Henderson Group
United Kingdom
$49M -$10.2M -31,228 -17%
Fidelity International
82
Fidelity International
Bermuda
$48.2M +$9.81M +30,075 +26%
DM
83
Deerfield Management
New York
$47.3M – – –
BNP Paribas Financial Markets
84
BNP Paribas Financial Markets
France
$41.9M +$28.1M +86,059 +202%
CIS
85
Capital International Sarl
California
$41.8M +$2.32M +7,126 +6%
State Board of Administration of Florida Retirement System
86
State Board of Administration of Florida Retirement System
Florida
$41.4M +$590K +1,810 +1%
EAM
87
Eventide Asset Management
Massachusetts
$41.1M -$13.2M -40,548 -24%
AP
88
Antipodes Partners
Australia
$40M -$12M -36,750 -23%
WorldQuant Millennium Advisors
89
WorldQuant Millennium Advisors
New York
$38.3M -$24M -73,732 -39%
Balyasny Asset Management
90
Balyasny Asset Management
Illinois
$37.6M +$33.3M +102,159 +779%
Universal-Beteiligungs- und Servicegesellschaft
91
Universal-Beteiligungs- und Servicegesellschaft
Germany
$37.3M -$1.09M -3,354 -3%
DekaBank Deutsche Girozentrale
92
DekaBank Deutsche Girozentrale
Germany
$36.5M +$48.7K +151 +0.1%
Mitsubishi UFJ Asset Management
93
Mitsubishi UFJ Asset Management
Japan
$36.5M +$1.93M +5,906 +6%
Korea Investment Corp
94
Korea Investment Corp
South Korea
$36.1M +$1.66M +5,096 +5%
HighTower Advisors
95
HighTower Advisors
Illinois
$35.6M -$1.5M -4,592 -4%
D.E. Shaw & Co
96
D.E. Shaw & Co
New York
$35.3M -$59.2M -181,586 -63%
SCM
97
Soleus Capital Management
Connecticut
$34.8M +$34.8M +106,750 New
FCM
98
Frontier Capital Management
Massachusetts
$33.6M +$190K +583 +0.6%
Ensign Peak Advisors
99
Ensign Peak Advisors
Utah
$32.7M +$6.43M +19,730 +25%
RSCM
100
Rock Springs Capital Management
Maryland
$32.6M -$14.1M -43,250 -30%
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