ALNY icon

Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
926
Telos Capital Management
California
FCM
927
Fourpath Capital Management
Oklahoma
GCP
928
GSA Capital Partners
United Kingdom
ABTD
929
Arvest Bank Trust Division
Oklahoma
RA
930
Riversedge Advisors
Delaware
C
931
Certuity
Florida
AFGAS
932
Allegiance Financial Group Advisory Services
Virginia
AO
933
Advisor OS
Illinois
DWT
934
Dorsey & Whitney Trust
South Dakota
BHB
935
Bank Hapoalim BM
Israel
KCM
936
KRS Capital Management
Michigan
IAS
937
Insigneo Advisory Services
Florida
RWM
938
Ritholtz Wealth Management
New York
IWA
939
Icon Wealth Advisors
Texas
EDRH
940
Edmond de Rothschild Holding
Switzerland
AAS
941
Ameritas Advisory Services
Nebraska
NFSG
942
Newbridge Financial Services Group
Florida
ACM
943
Aster Capital Management
United Arab Emirates
CIAM
944
Caitong International Asset Management
Hong Kong
JWM
945
JPL Wealth Management
Colorado
PPA
946
Painted Porch Advisors
California
PAM
947
Palisade Asset Management
Minnesota
HHGA
948
Halbert Hargrove Global Advisors
California
WANY
949
Wealthspire Advisors (New York)
New York
EPW
950
Evergreen Private Wealth
Colorado