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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
926
TABR Capital Management
California
KPWS
927
Kestra Private Wealth Services
Texas
HL
928
HeadInvest LLC
Maine
LAM
929
Longboard Asset Management
Arizona
NAS
930
NWF Advisory Services
California
MK
931
MASTERINVEST Kapitalanlage
PCP
932
Proficio Capital Partners
Massachusetts
TCM
933
Telos Capital Management
California
FCM
934
Fourpath Capital Management
Oklahoma
GCP
935
GSA Capital Partners
United Kingdom
ABTD
936
Arvest Bank Trust Division
Oklahoma
RA
937
Riversedge Advisors
Delaware
C
938
Certuity
Florida
AFGAS
939
Allegiance Financial Group Advisory Services
Virginia
AO
940
Advisor OS
Illinois
DWT
941
Dorsey & Whitney Trust
South Dakota
BHB
942
Bank Hapoalim BM
Israel
KCM
943
KRS Capital Management
Michigan
IAS
944
Insigneo Advisory Services
Florida
RWM
945
Ritholtz Wealth Management
New York
IWA
946
Icon Wealth Advisors
Texas
EDRH
947
Edmond de Rothschild Holding
Switzerland
AAS
948
Ameritas Advisory Services
Nebraska
NFSG
949
Newbridge Financial Services Group
Florida
ACM
950
Aster Capital Management
United Arab Emirates