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Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
901
Requisite Capital Management
Texas
BBA
902
Baader Bank Aktiengesellschaft
Germany
KCP
903
Kera Capital Partners
California
Polen Capital Management
904
Polen Capital Management
Florida
RL
905
Retireful LLC
Michigan
SWGC
906
Summit Wealth Group (Colorado)
Colorado
MWM
907
Moran Wealth Management
Florida
QFW
908
QTR Family Wealth
Florida
CPRC
909
Consolidated Portfolio Review Corp
New York
HI
910
Humankind Investments
New York
CRIG
911
Charter Research & Investment Group
Connecticut
BIAS
912
Beacon Investment Advisory Services
New Jersey
SCM
913
Stevens Capital Management
Pennsylvania
AA
914
Armis Advisers
Georgia
FMLI
915
Fukoku Mutual Life Insurance
Japan
Capital International Investors
916
Capital International Investors
California
FA
917
Fiduciary Alliance
South Carolina
KPWS
918
Kestra Private Wealth Services
Texas
AWAU
919
Alliance Wealth Advisors (Utah)
Utah
TCM
920
TABR Capital Management
California
LAM
921
Longboard Asset Management
Arizona
HL
922
HeadInvest LLC
Maine
NAS
923
NWF Advisory Services
California
MK
924
MASTERINVEST Kapitalanlage
PCP
925
Proficio Capital Partners
Massachusetts