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Alnylam Pharmaceuticals

832 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 283 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 283 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.57B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
832
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
QFW
901
QTR Family Wealth
Florida
CPRC
902
Consolidated Portfolio Review Corp
New York
HI
903
Humankind Investments
New York
CRIG
904
Charter Research & Investment Group
Connecticut
BIAS
905
Beacon Investment Advisory Services
New Jersey
SCM
906
Stevens Capital Management
Pennsylvania
FMLI
907
Fukoku Mutual Life Insurance
Japan
Capital International Investors
908
Capital International Investors
California
FA
909
Fiduciary Alliance
South Carolina
AWAU
910
Alliance Wealth Advisors (Utah)
Utah
TCM
911
TABR Capital Management
California
KPWS
912
Kestra Private Wealth Services
Texas
HL
913
HeadInvest LLC
Maine
LAM
914
Longboard Asset Management
Arizona
MK
915
MASTERINVEST Kapitalanlage
PCP
916
Proficio Capital Partners
Massachusetts
TCM
917
Telos Capital Management
California
FCM
918
Fourpath Capital Management
Oklahoma
GCP
919
GSA Capital Partners
United Kingdom
ABTD
920
Arvest Bank Trust Division
Oklahoma
RA
921
Riversedge Advisors
Delaware
C
922
Certuity
Florida
AFGAS
923
Allegiance Financial Group Advisory Services
Virginia
AO
924
Advisor OS
Illinois
DWT
925
Dorsey & Whitney Trust
South Dakota