ALNY icon

Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
GSC
901
Ground Swell Capital
South Carolina
NP
902
NorthRock Partners
Minnesota
SP
903
SIH Partners
Delaware
YCG
904
Yeomans Consulting Group
Georgia
PCM
905
Peregrine Capital Management
Minnesota
CCC
906
Compass Capital Corp
Massachusetts
WAM
907
Weiss Asset Management
Massachusetts
RCM
908
Requisite Capital Management
Texas
BBA
909
Baader Bank Aktiengesellschaft
Germany
KCP
910
Kera Capital Partners
California
Polen Capital Management
911
Polen Capital Management
Florida
RL
912
Retireful LLC
Michigan
SWGC
913
Summit Wealth Group (Colorado)
Colorado
MWM
914
Moran Wealth Management
Florida
QFW
915
QTR Family Wealth
Florida
CPRC
916
Consolidated Portfolio Review Corp
New York
HI
917
Humankind Investments
New York
BIAS
918
Beacon Investment Advisory Services
New Jersey
CRIG
919
Charter Research & Investment Group
Connecticut
SCM
920
Stevens Capital Management
Pennsylvania
AA
921
Armis Advisers
Georgia
FMLI
922
Fukoku Mutual Life Insurance
Japan
Capital International Investors
923
Capital International Investors
California
FA
924
Fiduciary Alliance
South Carolina
AWAU
925
Alliance Wealth Advisors (Utah)
Utah