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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
IBOK
826
Independence Bank of Kentucky
Kentucky
$1.19K
IPS
827
Investors Portfolio Services
Washington
$1.13K
OAJ
828
Ogorek Anthony Joseph
New York
$1K
PEAK6
829
PEAK6
Illinois
$866
RWS
830
Retirement Wealth Solutions
Wisconsin
$796
BIM
831
Breakwater Investment Management
Washington
$796
QWM
832
Quaker Wealth Management
New Jersey
$796
AWA
833
Acumen Wealth Advisors
Tennessee
$796
CFD
834
Creative Financial Designs
Indiana
$795
BGA
835
Battery Global Advisors
Massachusetts
$795
CTC
836
Central Trust Company
Missouri
$553
BFS
837
Bare Financial Services
Pennsylvania
$398
RJA
838
Ross\Johnson & Associates
Minnesota
$398
DCM
839
Davis Capital Management
Florida
$398
SA
840
Seneschal Advisors
Washington
$398
FC
841
Financial Consulate
Maryland
$398
APW
842
Atlantic Private Wealth
North Carolina
$398
HCM
843
Hollencrest Capital Management
California
$398
CCM
844
Chilton Capital Management
Texas
$398
GEA
845
Glen Eagle Advisors
New Jersey
$398
MI
846
Motiv8 Investments
Florida
$3
RP
847
Regeneron Pharmaceuticals
New York
HF
848
HRT Financial
New York
SAG
849
Susquehanna Advisors Group
Pennsylvania
ACM
850
Aquatic Capital Management
Illinois