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Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
OC
801
Optima Capital
Oregon
$1.99K
MA
802
Montag & Associates
Georgia
$1.86K
AWM
803
Abound Wealth Management
Tennessee
$1.73K
WW
804
Winnow Wealth
Texas
$1.59K
BHWM
805
Beaird Harris Wealth Management
Texas
$1.59K
ACA
806
American Capital Advisory
Idaho
$1.59K
GWS
807
Greykasell Wealth Strategies
California
$1.59K
JWM
808
Jessup Wealth Management
Ohio
$1.59K
JFA
809
JNBA Financial Advisors
Minnesota
$1.59K
UFPG
810
United Financial Planning Group
New York
$1.59K
PUI
811
Purpose Unlimited Inc
$1.59K
Kayne Anderson Rudnick Investment Management
812
Kayne Anderson Rudnick Investment Management
California
$1.44K
WWA
813
Wealth Watch Advisors
Colorado
$1.19K
RWM
814
Rialto Wealth Management
New York
$1.19K
TPCW
815
TD Private Client Wealth
New York
$1.19K
IBOK
816
Independence Bank of Kentucky
Kentucky
$1.19K
MHR
817
Matthew Hamilton Rosenberg
$1.19K
DT
818
DV Trading
Illinois
$1.19K
FCAS
819
First Command Advisory Services
Texas
$1.19K
IPS
820
Investors Portfolio Services
Washington
$1.13K
OAJ
821
Ogorek Anthony Joseph
New York
$1K
PEAK6
822
PEAK6
Illinois
$866
RWS
823
Retirement Wealth Solutions
Wisconsin
$796
QWM
824
Quaker Wealth Management
New Jersey
$796
BIM
825
Breakwater Investment Management
Washington
$796