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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
ADL
801
Asset Dedication LLC
California
$1.99K
CIAS
802
CBIZ Investment Advisory Services
Ohio
$1.99K
NRG
803
Nemes Rush Group
Michigan
$1.99K
DF
804
Dunhill Financial
United Kingdom
$1.99K
HNW
805
High Note Wealth
Minnesota
$1.99K
LWM
806
Lodestone Wealth Management
Washington
$1.99K
OC
807
Optima Capital
Oregon
$1.99K
MA
808
Montag & Associates
Georgia
$1.86K
AWM
809
Abound Wealth Management
Tennessee
$1.73K
WW
810
Winnow Wealth
Texas
$1.59K
GWS
811
Greykasell Wealth Strategies
California
$1.59K
BHWM
812
Beaird Harris Wealth Management
Texas
$1.59K
ACA
813
American Capital Advisory
Idaho
$1.59K
JFA
814
JNBA Financial Advisors
Minnesota
$1.59K
JWM
815
Jessup Wealth Management
Ohio
$1.59K
UFPG
816
United Financial Planning Group
New York
$1.59K
PUI
817
Purpose Unlimited Inc
$1.59K
Kayne Anderson Rudnick Investment Management
818
Kayne Anderson Rudnick Investment Management
California
$1.44K
WWA
819
Wealth Watch Advisors
Colorado
$1.19K
TPCW
820
TD Private Client Wealth
New York
$1.19K
RWM
821
Rialto Wealth Management
New York
$1.19K
MHR
822
Matthew Hamilton Rosenberg
$1.19K
DT
823
DV Trading
Illinois
$1.19K
FCAS
824
First Command Advisory Services
Texas
$1.19K
1CP
825
1015 Capital Partners
Pennsylvania
$1.19K