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Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
BHWM
776
Bay Harbor Wealth Management
Maryland
$3.58K
WTA
777
Washington Trust Advisors
Massachusetts
$3.42K
DPW
778
DiNuzzo Private Wealth
Pennsylvania
$3.18K
FPF
779
First Pacific Financial
Washington
$3.18K
NS
780
NBC Securities
Alabama
$3.18K
HWP
781
Highline Wealth Partners
California
$3.18K
SRCM
782
Signature Resources Capital Management
California
$3.18K
PCM
783
Penserra Capital Management
California
$3K
JFGIW
784
Johnson Financial Group Inc (Wisconsin)
Wisconsin
$2.78K
FRA
785
Front Row Advisors
California
$2.78K
CHC
786
City Holding Co
West Virginia
$2.78K
AF
787
Advisornet Financial
Minnesota
$2.39K
PWA
788
Principia Wealth Advisory
Texas
$2.39K
ANBT
789
American National Bank & Trust
Texas
$2.39K
EWP
790
Elevation Wealth Partners
California
$2.39K
SGK
791
Steigerwald Gordon & Koch
Virginia
$2.39K
SEP
792
Signature Equity Partners
Ohio
$2.39K
WCM
793
Winthrop Capital Management
Indiana
$2K
CI
794
CX Institutional
Indiana
$2K
ADL
795
Asset Dedication LLC
California
$1.99K
CIAS
796
CBIZ Investment Advisory Services
Ohio
$1.99K
HNW
797
High Note Wealth
Minnesota
$1.99K
LWM
798
Lodestone Wealth Management
Washington
$1.99K
DF
799
Dunhill Financial
United Kingdom
$1.99K
NRG
800
Nemes Rush Group
Michigan
$1.99K